Lipoproteins are complex substances containing lipids and specific proteins called apolipoproteins or apoproteins.
Lipoprotein particles include chylomicrons, high-density lipoproteins (HDL), very low-density lipoproteins (VLDL), intermediate low-density lipoproteins (IDL), and low-density lipoproteins (LDL).
Each of these particles differs in their lipid and protein composition, density and size, and site of origin. Lipoproteins act as transporter of lipids and render the lipids as water-soluble. Each lipoprotein is described in terms of their origin and metabolism in the following sections.
Chylomicrons are assembled in the intestinal cells, and they carry the dietary triacylglycerol, cholesterol, fat-soluble vitamins, and cholesterol esters to the peripheral tissues of the body. Chylomicrons are highest in their lipid content and lowest in density as compared to other lipoproteins. The characteristic apolipoprotein associated with...
References and Further Reading
- Harvey, R. A., & Ferrier, D. R. (2008). Cholesterol and steroid metabolism. In R. A. Harvey (Ed.), Lippincott’s illustrated reviews biochemistry (pp. 219–244). Philadelphia: Wolters Kluwer/Lippincott.Google Scholar