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Lipid, Plasma

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Encyclopedia of Behavioral Medicine

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Synonyms

Total cholesterol in the blood

Definition

Plasma lipid is the cholesterol content in the blood. Plasma lipid profile includes total cholesterol, triglycerides (TG), high-density lipoproteins (HDL), intermediate-density lipoproteins (IDL), low-density lipoproteins (LDL), and very low-density lipoproteins (VLDL). The fasting lipid profile is generally recommended due to significant variations in the TG levels due to food contents.

Elevated LDL cholesterol levels and lower levels of HDL are associated with increased risk for incident cardiovascular disease. Non-HDL cholesterol is calculated as the difference between total cholesterol and HDL levels. Non-HDL cholesterol includes all the cholesterol present in the lipoproteins attributed to atherogenicity. Non-HDL cholesterol is considered as better tool for risk assessment than the assessing LDL cholesterol alone.

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References and Further Reading

  • Cui, Y., Blumenthal, R. S., Flaws, J. A., Whiteman, M. K., Langenberg, P., Bachorik, P. S., et al. (2001). Non-high-density lipoprotein cholesterol level as a predictor of cardiovascular disease mortality. Archives of Internal Medicine, 161(11), 1413–1419.

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  • Friedewald, W. T., Levy, R. I., & Fredrickson, D. S. (1972). Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clinical Chemistry, 18(6), 499–502.

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  • Harvey, R. A., & Ferrier, D. R. (2008). Metabolism of lipids. In R. A. Harvey (Ed.), Lippincott’s illustrated reviews biochemistry (pp. 173–180). Philadelphia: Wolters Kluwer/Lippincott.

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  • Third Report of the National Cholesterol Education Program (NCEP). (2002). Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III) final report. Circulation, 106(25), 3143–3421.

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Center of Behavioral Cardiovascular Health, Division of General Medicine, Columbia University, New York, NY, USA

    Manjunath Harlapur

  2. Center for Behavioral Cardiovascular Health, Columbia University, New York, NY, USA

    Daichi Shimbo

Authors
  1. Manjunath Harlapur
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  2. Daichi Shimbo
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Corresponding author

Correspondence to Manjunath Harlapur .

Editor information

Editors and Affiliations

  1. University of Miami School of Medicine, Miami, FL, USA

    Marc Gellman

Section Editor information

  1. School of Nursing, University of Wisconsin-Madison, Madison, WI, USA

    Linda C. Baumann

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Harlapur, M., Shimbo, D. (2019). Lipid, Plasma. In: Gellman, M. (eds) Encyclopedia of Behavioral Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6439-6_1275-2

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  • DOI: https://doi.org/10.1007/978-1-4614-6439-6_1275-2

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  • Print ISBN: 978-1-4614-6439-6

  • Online ISBN: 978-1-4614-6439-6

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