Plasma lipid is the cholesterol content in the blood. Plasma lipid profile includes total cholesterol, triglycerides (TG), high-density lipoproteins (HDL), intermediate-density lipoproteins (IDL), low-density lipoproteins (LDL), and very low-density lipoproteins (VLDL). The fasting lipid profile is generally recommended due to significant variations in the TG levels due to food contents.
Elevated LDL cholesterol levels and lower levels of HDL are associated with increased risk for incident cardiovascular disease. Non-HDL cholesterol is calculated as the difference between total cholesterol and HDL levels. Non-HDL cholesterol includes all the cholesterol present in the lipoproteins attributed to atherogenicity. Non-HDL cholesterol is considered as better tool for risk assessment than the assessing LDL cholesterol alone.
References and Further Reading
- Harvey, R. A., & Ferrier, D. R. (2008). Metabolism of lipids. In R. A. Harvey (Ed.), Lippincott’s illustrated reviews biochemistry (pp. 173–180). Philadelphia: Wolters Kluwer/Lippincott.Google Scholar