Encyclopedia of Behavioral Medicine

Living Edition
| Editors: Marc Gellman

Lipid, Plasma

  • Manjunath HarlapurEmail author
  • Daichi Shimbo
Living reference work entry
DOI: https://doi.org/10.1007/978-1-4614-6439-6_1275-2



Plasma lipid is the cholesterol content in the blood. Plasma lipid profile includes total cholesterol, triglycerides (TG), high-density lipoproteins (HDL), intermediate-density lipoproteins (IDL), low-density lipoproteins (LDL), and very low-density lipoproteins (VLDL). The fasting lipid profile is generally recommended due to significant variations in the TG levels due to food contents.

Elevated LDL cholesterol levels and lower levels of HDL are associated with increased risk for incident cardiovascular disease. Non-HDL cholesterol is calculated as the difference between total cholesterol and HDL levels. Non-HDL cholesterol includes all the cholesterol present in the lipoproteins attributed to atherogenicity. Non-HDL cholesterol is considered as better tool for risk assessment than the assessing LDL cholesterol alone.


References and Further Reading

  1. Cui, Y., Blumenthal, R. S., Flaws, J. A., Whiteman, M. K., Langenberg, P., Bachorik, P. S., et al. (2001). Non-high-density lipoprotein cholesterol level as a predictor of cardiovascular disease mortality. Archives of Internal Medicine, 161(11), 1413–1419.CrossRefGoogle Scholar
  2. Friedewald, W. T., Levy, R. I., & Fredrickson, D. S. (1972). Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clinical Chemistry, 18(6), 499–502.PubMedGoogle Scholar
  3. Harvey, R. A., & Ferrier, D. R. (2008). Metabolism of lipids. In R. A. Harvey (Ed.), Lippincott’s illustrated reviews biochemistry (pp. 173–180). Philadelphia: Wolters Kluwer/Lippincott.Google Scholar
  4. Third Report of the National Cholesterol Education Program (NCEP). (2002). Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III) final report. Circulation, 106(25), 3143–3421.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Center of Behavioral Cardiovascular Health, Division of General MedicineColumbia UniversityNew YorkUSA
  2. 2.Center for Behavioral Cardiovascular HealthColumbia UniversityNew YorkUSA

Section editors and affiliations

  • Linda C. Baumann
    • 1
  1. 1.School of NursingUniversity of Wisconsin-MadisonMadisonUSA