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Definition
Anxiety is an emotional response to a situation, which has both psychological and physiological consequences. Anxiety may be a normal response to daily life situations. However, a heightened or an inappropriate level of anxiety may lead to several deleterious consequences to overall health. There is mounting research about the role of anxiety in the pathophysiology of heart disease.
Description
In the past decade, there has been increasing interest in the relationship between anxiety and heart disease. As reviewed by Rozanski et al. (1999) prior to 1999, there were a limited number of prospective studies demonstrating a relationship between anxiety and subsequent cardiovascular disease (CVD) outcomes in healthy populations and in patients with prevalent CVD.
After these initial studies, additional prospective studies examining the relationship between anxiety and CVD outcomes in participants without prior CVD history have been...
References and Further Reading
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Doering, L. V., Moser, D. K., Riegel, B., McKinley, S., Davidson, P., Baker, H., Meischke, H., & Dracup, K. (2010). Persistent comorbid symptoms of depression and anxiety predict mortality in heart disease. International Journal of Cardiology, 145, 188–192.
Huffman, J. C., Smith, F. A., Blais, M. A., Jannuzzi, J. L., & Fricchione, G. L. (2008). Anxiety, independent of depressive symptoms, is associated with in-hospital cardiac complications after acute myocardial infarction. Journal of Psychosomatic Research, 65, 557–563.
Janszky, I., Ahnve, S., Lundberg, I., & Hemmingsson, T. (2010). Early-onset depression, anxiety, and risk of subsequent coronary heart disease: 37-year follow-up of 49,321 young Swedish men. Journal of the American College of Cardiology, 56, 31–37.
Martins, E. J., de Jonge, P., Beeya, N. A., Cohen, B. E., & Whooley, M. A. (2010). Scared to death? Generalized anxiety disorder and cardiovascular events in patients with stable coronary heart disease: The heart and soul study. Archives of General Psychiatry, 67(7), 750–758.
Roest, A. M., Martens, E. J., de Jonge, P., & Denollet, J. (2010a). Anxiety and risk of incident coronary heart disease: A meta-analysis. Journal of the American College of Cardiology, 56, 38–46.
Roest, A. M., Martens, E. J., Denollet, J., & Jonge, P. (2010b). Prognostic association of anxiety post myocardial infarction with mortality and new cardiac events: A meta-analysis. Psychosomatic Medicine, 72, 563–569.
Rozanski, A., Blumenthal, J. A., & Kaplan, J. (1999). Impact of psychological factors on the pathogenesis of cardiovascular disease and implications for therapy. Circulation, 99, 2192–2217.
Shen, B. J., Avivi, Y. E., Todaro, J. F., Spiro, A., III, Laurenceau, J.-P., Ward, K. D., et al. (2008). Anxiety characteristics independently and prospectively predict myocardial infarction in men: The unique contribution of anxiety among psychologic factors. Journal of the American College of Cardiology, 51, 113–119.
Shibeshi, W. A., Young-Zu, Y., & Blatt, C. M. (2007). Anxiety worsens prognosis in patients with coronary artery disease. Journal of the American College of Cardiology, 49, 2021–2027.
Strik, J. M. H., Denollet, J. K. L., Lousberg, R., & Honig, A. (2003). Comparing symptoms of depression and anxiety as predictors of cardiac events and increased health care consumption after myocardial infarction. Journal of the American College of Cardiology, 42(10), 1801–1807.
van den Broek, K. C., Nyklicek, I., van der Voort, P. H., Alings, M., Meijer, A., & Denollet, J. (2009). Risk of ventricular arrhythmia after implantable defibrillator treatment in anxious type D patients. Journal of the American College of Cardiology, 54(6), 531–537.
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Harlapur, M., Shimbo, D. (2019). Anxiety and Heart Disease. In: Gellman, M. (eds) Encyclopedia of Behavioral Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6439-6_1248-2
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DOI: https://doi.org/10.1007/978-1-4614-6439-6_1248-2
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