Acute myocardial infarction (AMI), also known as heart attack or acute coronary syndrome (ACS), is a clinical condition that occurs when blood flow to regions of the heart is suddenly interrupted, causing myocardial ischemia and eventually cell death. Most commonly this is caused by coronary atherosclerosis and is initiated by the rupture or erosion of a complex, lipid-laden plaque that then triggers thrombus formation causing the total or subtotal occlusion of the coronary artery in question. Rarely, non-atherosclerotic processes such as vasospasm, vasculitis, and spontaneous coronary artery dissection may also lead to myocardial infarction.
Acute myocardial infarction is further classified into ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI), depending on the presence of ST-segment elevation on the 12-lead electrocardiogram (ECG). ST-segment elevation is typically associated with thrombi that are completely occlusive, leading to a large...
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Ye, S. (2018). Acute Myocardial Infarction. In: Gellman, M. (eds) Encyclopedia of Behavioral Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6439-6_1243-2
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