Encyclopedia of Behavioral Medicine

Living Edition
| Editors: Marc Gellman

National Children’s Study

  • Steven E. LipshultzEmail author
  • Tracie L. Miller
  • James D. Wilkinson
  • Miriam A. Mestre
Living reference work entry
DOI: https://doi.org/10.1007/978-1-4614-6439-6_1200-2



Definition (and Description)

The National Children’s Study (NCS) was planned to be the largest, longitudinal study of US children and their parents. It was designed to be “the first large birth cohort study in any nation to specifically examine the influence of environmental factors on birth outcomes, child health, and human development and the first designed to systematically examine the influence of gene-environment interactions on children’s health.” (Landrigan et al. 2006). It was authorized by the Children’s Health Act of 2000 and led by the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health (NIH) in collaboration with a consortium of federal government partners. The NCS Vanguard (Pilot) Study began in 2009, testing methods and procedures planned for use in a larger Main Study. When recruitment ended in July 2013, the Vanguard Study had enrolled approximately 5,000 children in 40 locations across the country. The planned NCS Main Study aimed to follow 100,000 children from before birth to 21years of age. After several years of piloting, the Main Study had still not been launched and on December 12, 2014, the NIH Director decided to close the study following the advice of an expert review group.

References and Further Reading

  1. Landrigan, P. J., et al. (2006). The National Children’s Study: A 21-year prospective study of 100 000 American children. Pediatrics, 118, 2173–2186. Retrieved from www.nationalchildrensstudy.gov.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Steven E. Lipshultz
    • 1
    • 2
    Email author
  • Tracie L. Miller
    • 3
  • James D. Wilkinson
    • 1
  • Miriam A. Mestre
    • 4
  1. 1.Wayne State University School of MedicineDetroitUSA
  2. 2.University of Miami Leonard M. Miller School of MedicineMiamiUSA
  3. 3.Department of Pediatrics and Epidemiology and Public Health Division of Pediatric Clinical Research Department of PediatricsLeonard M. Miller School of Medicine University of Miami Holtz Children’s Hospital of the University of Miami-Jackson Memorial Medical Center Batchelor Children’s Research Institute University of Miami Sylvester Comprehensive Cancer CenterMiamiUSA
  4. 4.Department of PediatricsWayne State University School of MedicineDetroitUSA

Section editors and affiliations

  • Alan M. Delamater
    • 1
  1. 1.Department of PediatricsUniversity of Miami Miller School of MedicineMiamiUSA