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References
Anand S, Penrhyn-Lowe S, Venkitaraman AR. AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol. Cancer Cell. 2003;3(1):51–62.
Anderson K, Yang J, Koretke K, Nurse K, Calamary A, Kirkpatrick RB, Patrick D, Silva D, Tummino PJ, Copeland RA, Lai Z. Biochemistry. 2007;46:10287–95.
Bavetsias V, Linardopoulos S. Aurora kinase inhibitors: current status and outlook. Frontiers in oncology. 2015;5:278.
Bayliss R, Sardon T, Vernos I, Conti E. Structural basis of aurora-A activation by TPX2 at the mitotic spindle. Mol Cell. 2003;12(4):851–62.
Boss DS, Beijnen JH, Schellens JH. Clinical experience with aurora kinase inhibitors: a review. Oncologist. 2009;14(8):780–93.
Caous R, Pascal A, Rome P, Richard-Parpaillon L, Karess R, Giet R. Spindle assembly checkpoint inactivation fails to suppress neuroblast tumour formation in aurA mutant Drosophila. Nat Commun. 2015;6:8879.
Chan CS, Botstein D. Isolation and characterization of chromosome-gain and increase-in-ploidy mutants in yeast. Genetics. 1993;135(3):677–91.
Glover DM, Leibowitz MH, McLean DA, Parry H. Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles. Cell. 1995;81(1):95–105.
Hans F, Skoufias DA, Dimitrov S, Margolis RL. Molecular distinctions between aurora A and B: a single residue change transforms aurora A into correctly localized and functional aurora B. Mol Biol Cell. 2009;20(15):3491–502.
Hegarat N, Smith E, Nayak G, Takeda S, Eyers PA, Hochegger H. Aurora A and Aurora B jointly coordinate chromosome segregation and anaphase microtubule dynamics. J Cell Biol. 2011;195:1103–13.
Karthigeyan D, Prasad SB, Shandilya J, Agrawal S, Kundu TK. Biology of aurora A kinase: implications in cancer manifestation and therapy. Med Res Rev. 2010;31:757–93.
Lioutas A, Vernos I. Aurora A kinase and its substrate TACC3 are required for central spindle assembly. EMBO Rep. 2013;14:829–36.
Marumoto T, Honda S, Hara T, Nitta M, Hirota T, Kohmura E, Saya H. Aurora-A kinase maintains the fidelity of early and late mitotic events in HeLa cells. J Biol Chem. 2003;278(51):61786–95.
Meraldi P, Honda R, Nigg EA. Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53−/− cells. EMBO J. 2002;21(4):483–92.
Nigg EA. Mitotic kinases as regulators of cell division and its checkpoints. Nat Rev Mol Cell Biol. 2001;2(1):21–32.
Norden C, Mendoza M, Dobbelaere J, Kotwaliwale CV, Biggins S, Barral Y. The NoCut pathway links completion of cytokinesis to spindle midzone function to prevent chromosome breakage. Cell. 2006;125(1):85–98.
Rannou Y, Troadec MB, Petretti C, Hans F, Dutertre S, Dimitrov S, Prigent C. Localization of aurora A and aurora B kinases during interphase: role of the N-terminal domain. Cell Cycle. 2008;7(19):3012–20.
Reboutier D, Troadec MB, Cremet JY, Chauvin L, Guen V, Salaun P, Prigent C. Aurora A is involved in central spindle assembly through phosphorylation of Ser 19 in P150Glued. J Cell Biol. 2013;201:65–79.
Vader G, Lens SM. The aurora kinase family in cell division and cancer. Biochim Biophys Acta. 2008;1786(1):60–72.
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Reboutier, D., Prigent, C. (2016). Aurora Kinases. In: Choi, S. (eds) Encyclopedia of Signaling Molecules. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6438-9_81-1
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DOI: https://doi.org/10.1007/978-1-4614-6438-9_81-1
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