Aurora Kinases Family Members and their Synonyms
Aurora-A: AIK, ARK1, AURA, AURORA2, BTAK, MGC34538, STK15, STK6, STK7
Aurora-B: AIK2, AIM-1, AIM1, ARK2, AurB, IPL1, STK12, STK5
Aurora-C: AIE2, AIK3, ARK3, AurC, STK13, Aurora-C
Every new cell is generated through division of an existing cell (one cell generates two cells), and survival of all organisms depends on reliable transmission of the genetic information from the mother cell to daughter cells. Consequently, all cellular components must be duplicated before cell divides, and these duplications must be achieved with extreme precision and reliability over generations. The eukaryotic cell (cell with a nucleus) has set up complex network of regulatory mechanisms to ensure a correct sequence of events that eventually leads to cell division. This network called the cell cycle control system consists mainly in a complex assembly of oscillating phosphorylation/dephosphorylation reactions. Several protein kinases and...
KeywordsAurora Kinase Spindle Assembly Checkpoint Centrosome Amplification Chromosomal Passenger Complex Aurora Kinase Inhibitor
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