Encyclopedia of Signaling Molecules

Living Edition
| Editors: Sangdun Choi

Aurora Kinases

Living reference work entry
DOI: https://doi.org/10.1007/978-1-4614-6438-9_81-1

Aurora Kinases Family Members and their Synonyms

Aurora-A: AIK, ARK1, AURA, AURORA2, BTAK, MGC34538, STK15, STK6, STK7

Aurora-B: AIK2, AIM-1, AIM1, ARK2, AurB, IPL1, STK12, STK5

Aurora-C: AIE2, AIK3, ARK3, AurC, STK13, Aurora-C

Historical Background

Every new cell is generated through division of an existing cell (one cell generates two cells), and survival of all organisms depends on reliable transmission of the genetic information from the mother cell to daughter cells. Consequently, all cellular components must be duplicated before cell divides, and these duplications must be achieved with extreme precision and reliability over generations. The eukaryotic cell (cell with a nucleus) has set up complex network of regulatory mechanisms to ensure a correct sequence of events that eventually leads to cell division. This network called the cell cycle control system consists mainly in a complex assembly of oscillating phosphorylation/dephosphorylation reactions. Several protein kinases and...


Aurora Kinase Spindle Assembly Checkpoint Centrosome Amplification Chromosomal Passenger Complex Aurora Kinase Inhibitor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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© Springer Science+Business Media LLC 2016

Authors and Affiliations

  1. 1.Centre National de la Recherche Scientifique, Unité Mixte de Recherche 6290RennesFrance
  2. 2.Université Rennes 1, Institut de Génétique et Développement de RennesRennesFrance