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Proteinase-Activated Receptors (PARs)

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Encyclopedia of Signaling Molecules

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Synonyms

PAR 1 : CF2R; Coagulation factor II thrombin receptor; Coagulation factor II (thrombin) receptor; HTR; Proteinase-activated receptor 1; Proteinase-activated receptor 1; PAR1; PAR-1; Thrombin receptor TR

PAR 2 : F2RL1; F2R-like trypsin receptor 1; GPR11; Proteinase-activated receptor 2; Proteinase-activated receptor 2; PAR2; PAR-2

PAR 3 : Coagulation factor II thrombin receptor-like 2; Coagulation factor II (thrombin) receptor-like 2; F2RL2; Proteinase-activated receptor 3; Proteinase-activated receptor 3; PAR3; PAR-3; Thrombin receptor-like 2

PAR 4 : Coagulation factor II (thrombin) receptor-like 3; Coagulation factor II receptor-like 3; F2RL3; F2R-like thrombin/trypsin receptor 3; PAR4; PAR-4; Proteinase-activated receptor 4; Proteinase-activated receptor 4; Thrombin receptor-like 3

Historical Background

Since about 50 years, serine proteinases like chymotrypsin and pepsin have been known to cause hormone-like effects in target tissues. In addition, in the 1970, thrombin and...

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Authors and Affiliations

  1. Department of General, Visceral and Vascular Surgery, Jena University Hospital, Am Klinikum 1, D-07747, Jena, Germany

    Roland Kaufmann & Utz Settmacher

  2. University of Lübeck, Lübeck, Germany

    Hendrik Ungefroren

Authors
  1. Roland Kaufmann
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  2. Utz Settmacher
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  3. Hendrik Ungefroren
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Corresponding author

Correspondence to Roland Kaufmann .

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Editors and Affiliations

  1. Dept. Biological Science, Department of Molecular Science and Tech College of Natural Science, Suwon, Korea (Republic of)

    Sangdun Choi

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Kaufmann, R., Settmacher, U., Ungefroren, H. (2016). Proteinase-Activated Receptors (PARs). In: Choi, S. (eds) Encyclopedia of Signaling Molecules. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6438-9_101885-1

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  • DOI: https://doi.org/10.1007/978-1-4614-6438-9_101885-1

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