Synopsis
Gene expression describes the flow of genetically encoded information from DNA to its intermediary form, mRNA, and its functional form, protein. In eukaryotes, mRNAs are co-transcriptionally highly processed from a precursor mRNA or pre-mRNA to a mature mRNA. To form mature mRNAs, the pre-mRNA’s 5′ end is capped, its coding regions are joined together during a process called pre-mRNA splicing, and its 3′ end is cleaved and appended with a poly(A) tail. By modifying pre-mRNAs, the cell is afforded multiple opportunities for regulatory control in the diversity and levels of an mRNA prior to its translation into protein.
Introduction
For all organisms, the expression of genes from DNA to functional protein requires first the transfer of information to a transient messenger RNA molecule known as mRNA. In prokaryotes, mRNAs are typically direct copies...
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Marvin, B., Inada, M. (2014). Co-transcriptional mRNA Processing in Eukaryotes. In: Bell, E. (eds) Molecular Life Sciences. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6436-5_41-4
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DOI: https://doi.org/10.1007/978-1-4614-6436-5_41-4
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Publisher Name: Springer, New York, NY
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