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Molecular Life Sciences pp 1–12Cite as

Gene Regulation

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Synopsis

One of the fundamental questions in biology is: How is gene expression regulated in a context-dependent manner such that appropriate phenotypes (e.g., RNA, proteins) are produced given different environmental conditions? Indeed, appropriate genetic regulation is the hallmark of cellular viability. In multicellular organisms, cells that share identical genomes produce different phenotypes depending on specific spatial and temporal signals, bacterial cells produce different proteins when metabolic changes occur in the environment, and stem cells become heart or brain cells only when appropriate triggers are detected. This introductory entry will provide an overview of gene regulation in prokaryotic and eukaryotic systems. The subsequent chapters will deal more specifically with a suite of mechanisms used by cellular organisms to regulate expression and mechanisms employed to control the processing and production of gene products.

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Author information

Authors and Affiliations

  1. Department of Biology, University of Richmond, 28 Westhampton Way, Richmond, VA, 23173, USA

    April Hill & Sarah Friday

Authors
  1. April Hill
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  2. Sarah Friday
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Corresponding author

Correspondence to April Hill .

Editor information

Editors and Affiliations

  1. Department of Chemistry, Texas A&M University, College Station, Texas, USA

    Robert D. Wells

  2. Biochemistry and Molecular Biology, Penn State College of Medicine, Hershey, Pennsylvania, USA

    Judith S. Bond

  3. Department of Chemistry Department of Molecular and Cell Biology, University of California The california institute for Quanti, Berkeley, California, USA

    Judith Klinman

  4. Department of Biochemistry, The University of Texas Health Science C, San Antonio, Texas, USA

    Bettie Sue Siler Masters

  5. Dept of Chemistry, University of Richmond, Richmond, Virginia, USA

    Ellis Bell

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© 2015 Springer Science+Business Media New York

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Hill, A., Friday, S. (2015). Gene Regulation. In: Wells, R., Bond, J., Klinman, J., Masters, B., Bell, E. (eds) Molecular Life Sciences. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6436-5_34-1

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  • DOI: https://doi.org/10.1007/978-1-4614-6436-5_34-1

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  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-6436-5

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

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