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Molecular Life Sciences pp 1–14Cite as

NMR Basis for Biomolecular Structure (Theory)

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Synonyms

Coherence transfer; Density matrix formalism; Multidimensional NMR; Nuclear magnetic resonance; Product operator formalism

Synopsis

Nuclear magnetic resonance (NMR) is referred to as a nucleus with spin under a magnetic field that will be excited by electromagnetic radiation with specific frequency (Larmor frequency). The resonance frequency variation depends on magnetic field strength, atom type, and the chemical environments the atom exists (chemical shift phenomenon). Chemical shift analysis can provide plenty of structure information of a molecule, but the overcrowd resonance signals in conventional (one-dimensional) spectra restricted its use on biomolecules. The superiority of modern NMR is to disperse the overcrowd resonance signals to multidimension. Density matrix formalism is the core of modern NMR, which mathematically describes the evolution of a nuclear spin system precisely. Product operator formalism, the simplified version of density matrix formalism, is more...

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Authors and Affiliations

  1. Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN, 55905, USA

    Gaofeng Cui

Authors
  1. Gaofeng Cui
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Corresponding author

Correspondence to Gaofeng Cui .

Editor information

Editors and Affiliations

  1. Dept of Chemistry, University of Richmond, Richmond, Virginia, USA

    Ellis Bell

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© 2014 Springer Science+Business Media New York

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Cui, G. (2014). NMR Basis for Biomolecular Structure (Theory). In: Bell, E. (eds) Molecular Life Sciences. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6436-5_31-2

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  • DOI: https://doi.org/10.1007/978-1-4614-6436-5_31-2

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  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-6436-5

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

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