Synopsis
Amoebozoa is a supergroup including the cellular (dictyostelid) and acellular (myxomycete) slime molds and the lobose amoebae, as well as several other groups of amoeboid protozoa. The mitochondrial DNAs (mtDNAs) from prototype organisms of each of these three groups have been completely sequenced and characterized. Although these mitochondrial genomes have a number of features in common as anticipated for related organisms, there is an unexpected similarity in mtDNA features between Acanthamoeba castellanii (lobose amoeba) and Dictyostelium discoideum (slime mold), while there are a surprising number of differences in mtDNA features between Physarum polycephalum and Dictyostelium discoideum (both slime molds). Similarities and differences in mtDNA size, gene content, and gene organization as well as mitochondrial gene expression are compared and contrasted. The evolutionary implications of these comparisons are discussed.
Introduction
Amoebozoa is a supergroup of eukaryotes...
References
Abad MG, Long Y, Willcox A, Gott JM, Gray MW, Jackman JE (2011) A role for tRNAHis guanylyltransferase (Thg1)-like proteins from Dictyostelium discoideum in mitochondrial 5′-tRNA editing. RNA 17:613–623
Antes T, Costandy H, Mahendran R, Spottswood M, Miller D (1998) Insertional editing of tRNAs of Physarum polycephalum and Didymium nigripes. Mol Cell Biol 18:7521–7527
Barth C, Greferath U, Kotsifas M, Fisher PR (1999) Polycistronic transcription and editing of the mitochondrial small subunit (SSU) ribosomal RNA in Dictyostelium discoideum. Curr Genet 36:55–61
Bullerwell CE, Burger G, Gott JM, Kourennaia O, Schnare MN, Gray MW (2010) Abundant 5S rRNA-like transcripts encoded by the mitochondrial genome in Amoebozoa. Eukaryot Cell 9:762–773
Bundschuh R, Antmuller J, Becker C, Nurnburg P, Gott JM (2011) Complete characterization of the edited transcriptome of the mitochondrion of Physarum polycephalum using deep sequencing of RNA. Nucleic Acids Res 39:6044–6055
Cheng YW, Visomirski-Robic LM, Gott JM (2001) Non-templated addition of nucleotides to the 3′ end of nascent RNA during RNA editing in Physarum. EMBO J 20:1405–1414
Gott JM, Somerlot BH, Gray MW (2010) Two forms of RNA editing are required for tRNA maturation in Physarum mitochondria. RNA 16:482–488
Gott JM, Visomirski LM, Hunter JL (1993) Substitutional and insertional RNA editing of the cytochrome c oxidase subunit 1 mRNA of Physarum polycephalum. J Biol Chem 268:25483–25486
Gray MW, Lang BF, Burger G (2004) Mitochondria of protists. Annu Rev Genet 38:477–524
Hendrickson PG, Silliker ME (2010) RNA editing is absent in a single mitochondrial gene of Didymium iridis. Mycologia 102:1288–1294
Krishnan U, Barsamian A, Miller DL (2007) Evolution of RNA editing sites in the mitochondrial small subunit rRNA of the myxomycetes. Methods Enzymol 424:197–220
Le P, Fisher PR, Barth C (2009) Transcription of the Dictyostelium discoideum mitochondrial genome occurs from a single initiation site. RNA 15:2321–2330
Miller ML, Miller DL (2008) Non-DNA-templated addition of nucleotides to the 3′ end of RNAs by the mitochondrial RNA polymerase of Physarum polycephalum. Mol Cell Biol 28:5795–5802
Nakagawa CC, Jones EP, Miller DL (1998) Mitochondrial DNA rearrangements associated with mF plasmid integration and plasmodial longevity in Physarum polycephalum. Curr Genet 33:178–187
Nomura H, Moriyama Y, Kawano S (2005) Rearrangements in the Physarum polycephalum mitochondrial genome associated with a transition from linear mF-mtDNA recombinants to circular molecules. Curr Genet 47:100–110
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer Science+Business Media New York
About this entry
Cite this entry
Miller, D. (2014). Mitochondrial Genomes in Amoebozoa. In: Bell, E. (eds) Molecular Life Sciences. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6436-5_114-2
Download citation
DOI: https://doi.org/10.1007/978-1-4614-6436-5_114-2
Received:
Accepted:
Published:
Publisher Name: Springer, New York, NY
Online ISBN: 978-1-4614-6436-5
eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences