Molecular Life Sciences

Living Edition
| Editors: Robert D. Wells, Judith S. Bond, Judith Klinman, Bettie Sue Siler Masters, Ellis Bell

Mitochondrial Genomes in Amoebozoa

Living reference work entry
DOI: https://doi.org/10.1007/978-1-4614-6436-5_114-2

Synopsis

Amoebozoa is a supergroup including the cellular (dictyostelid) and acellular (myxomycete) slime molds and the lobose amoebae, as well as several other groups of amoeboid protozoa. The mitochondrial DNAs (mtDNAs) from prototype organisms of each of these three groups have been completely sequenced and characterized. Although these mitochondrial genomes have a number of features in common as anticipated for related organisms, there is an unexpected similarity in mtDNA features between Acanthamoeba castellanii (lobose amoeba) and Dictyostelium discoideum (slime mold), while there are a surprising number of differences in mtDNA features between Physarum polycephalum and Dictyostelium discoideum (both slime molds). Similarities and differences in mtDNA size, gene content, and gene organization as well as mitochondrial gene expression are compared and contrasted. The evolutionary implications of these comparisons are discussed.

Introduction

Amoebozoa is a supergroup of eukaryotes...

Keywords

Mitochondrial Genome Editing Site Dictyostelium Discoideum Slime Mold Physarum Polycephalum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in to check access.

References

  1. Abad MG, Long Y, Willcox A, Gott JM, Gray MW, Jackman JE (2011) A role for tRNAHis guanylyltransferase (Thg1)-like proteins from Dictyostelium discoideum in mitochondrial 5′-tRNA editing. RNA 17:613–623PubMedCentralPubMedCrossRefGoogle Scholar
  2. Antes T, Costandy H, Mahendran R, Spottswood M, Miller D (1998) Insertional editing of tRNAs of Physarum polycephalum and Didymium nigripes. Mol Cell Biol 18:7521–7527PubMedCentralPubMedGoogle Scholar
  3. Barth C, Greferath U, Kotsifas M, Fisher PR (1999) Polycistronic transcription and editing of the mitochondrial small subunit (SSU) ribosomal RNA in Dictyostelium discoideum. Curr Genet 36:55–61PubMedCrossRefGoogle Scholar
  4. Bullerwell CE, Burger G, Gott JM, Kourennaia O, Schnare MN, Gray MW (2010) Abundant 5S rRNA-like transcripts encoded by the mitochondrial genome in Amoebozoa. Eukaryot Cell 9:762–773PubMedCentralPubMedCrossRefGoogle Scholar
  5. Bundschuh R, Antmuller J, Becker C, Nurnburg P, Gott JM (2011) Complete characterization of the edited transcriptome of the mitochondrion of Physarum polycephalum using deep sequencing of RNA. Nucleic Acids Res 39:6044–6055PubMedCentralPubMedCrossRefGoogle Scholar
  6. Cheng YW, Visomirski-Robic LM, Gott JM (2001) Non-templated addition of nucleotides to the 3′ end of nascent RNA during RNA editing in Physarum. EMBO J 20:1405–1414PubMedCentralPubMedCrossRefGoogle Scholar
  7. Gott JM, Somerlot BH, Gray MW (2010) Two forms of RNA editing are required for tRNA maturation in Physarum mitochondria. RNA 16:482–488PubMedCentralPubMedCrossRefGoogle Scholar
  8. Gott JM, Visomirski LM, Hunter JL (1993) Substitutional and insertional RNA editing of the cytochrome c oxidase subunit 1 mRNA of Physarum polycephalum. J Biol Chem 268:25483–25486PubMedGoogle Scholar
  9. Gray MW, Lang BF, Burger G (2004) Mitochondria of protists. Annu Rev Genet 38:477–524PubMedCrossRefGoogle Scholar
  10. Hendrickson PG, Silliker ME (2010) RNA editing is absent in a single mitochondrial gene of Didymium iridis. Mycologia 102:1288–1294PubMedCrossRefGoogle Scholar
  11. Krishnan U, Barsamian A, Miller DL (2007) Evolution of RNA editing sites in the mitochondrial small subunit rRNA of the myxomycetes. Methods Enzymol 424:197–220PubMedCrossRefGoogle Scholar
  12. Le P, Fisher PR, Barth C (2009) Transcription of the Dictyostelium discoideum mitochondrial genome occurs from a single initiation site. RNA 15:2321–2330PubMedCentralPubMedCrossRefGoogle Scholar
  13. Miller ML, Miller DL (2008) Non-DNA-templated addition of nucleotides to the 3′ end of RNAs by the mitochondrial RNA polymerase of Physarum polycephalum. Mol Cell Biol 28:5795–5802PubMedCentralPubMedCrossRefGoogle Scholar
  14. Nakagawa CC, Jones EP, Miller DL (1998) Mitochondrial DNA rearrangements associated with mF plasmid integration and plasmodial longevity in Physarum polycephalum. Curr Genet 33:178–187PubMedCrossRefGoogle Scholar
  15. Nomura H, Moriyama Y, Kawano S (2005) Rearrangements in the Physarum polycephalum mitochondrial genome associated with a transition from linear mF-mtDNA recombinants to circular molecules. Curr Genet 47:100–110PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Department of Molecular and Cell BiologyThe University of Texas at DallasRichardsonUSA