Molecular Life Sciences

Living Edition
| Editors: Robert D. Wells, Judith S. Bond, Judith Klinman, Bettie Sue Siler Masters, Ellis Bell

Mitochondrial Genomes in Amoebozoa

Living reference work entry


Amoebozoa is a supergroup including the cellular (dictyostelid) and acellular (myxomycete) slime molds and the lobose amoebae, as well as several other groups of amoeboid protozoa. The mitochondrial DNAs (mtDNAs) from prototype organisms of each of these three groups have been completely sequenced and characterized. Although these mitochondrial genomes have a number of features in common as anticipated for related organisms, there is an unexpected similarity in mtDNA features between Acanthamoeba castellanii (lobose amoeba) and Dictyostelium discoideum (slime mold), while there are a surprising number of differences in mtDNA features between Physarum polycephalum and Dictyostelium discoideum (both slime molds). Similarities and differences in mtDNA size, gene content, and gene organization as well as mitochondrial gene expression are compared and contrasted. The evolutionary implications of these comparisons are discussed.


Amoebozoa is a supergroup of eukaryotes...


Mitochondrial Genome Editing Site Dictyostelium Discoideum Slime Mold Physarum Polycephalum 
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© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Department of Molecular and Cell BiologyThe University of Texas at DallasRichardsonUSA