Encyclopedia of Autism Spectrum Disorders

Living Edition
| Editors: Fred R. Volkmar

Williams Syndrome

Living reference work entry
DOI: https://doi.org/10.1007/978-1-4614-6435-8_1629-5

Synonyms

Short Description or Definition

Williams syndrome (WS) is a neurodevelopmental disorder caused by a hemizygous deletion of approximately 25 genes on chromosome 7q.23. Although some variability is common, characteristic physical, cognitive, and personality profiles do exist within WS. Physical characteristics include dysmorphic facial features, short stature, musculoskeletal problems, and connective tissue abnormalities including congenital heart conditions. Cognitive features generally include impaired intellectual functioning (within the mild range of intellectual disability), with a marked weakness in visuospatial constructive abilities. Language development is typically delayed, but language abilities generally ultimately fall at the same level as overall functioning. Personality features include overfriendliness and sociability despite impaired social skills. Attention problems and anxiety are common.

Categorization

Results of FISH testing are used...

Keywords

Autism Spectrum Disorder Intellectual Disability Williams Syndrome Specific Language Impairment Fetal Alcohol Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References and Reading

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  1. 1.Department of PsychologyUniversity of Wisconsin, MilwaukeeMilwaukeeUSA