Irritability in children with autism spectrum disorder (ASD) has been a long-standing target of clinical research including pharmacological and behavioral interventions. Historically, the term irritability was used in ASD literature as an umbrella category for severe disruptive behaviors including temper tantrums, aggression, and noncompliance. The rates of co-occurrence of ASD with disruptive behavior disorders ranges from 16% to 37% for oppositional defiant and 2–9.6% for conduct disorder. However, up to 65% of children with ASD can have physically aggressive behavior towards their peers or caregivers. (Kanne and Mazurek 2011). Using a more recent conceptualization of irritability, as a cluster of mood symptoms, 45% of children with ASD were reported to have high levels of angry mood and temper tantrums (Mayes et al. 2017). Irritability and associated behavioral problems are distressing in their own right for children and families, and they also contribute to the gap between...
References and Reading
Aman, M. G., & Singh, N. N. (2017). Aberrant behavior checklist – Second edition (ABC-2). Wood Dale: Stoelting.
Aman, M. G., Singh, N. N., Stewart, A. W., & Field, C. J. (1985). The aberrant behavior checklist: A behavior rating scale for the assessment of treatment effects. American Journal of Mental Deficiency, 89(5), 485–491.
Aman, M. G., McDougle, C. J., Scahill, L., Handen, B., Arnold, L. E., Johnson, C., … Wagner, A. (2009). Medication and parent training in children with pervasive developmental disorders and serious behavior problems: Results from a randomized clinical trial. Journal of the American Academy of Child and Adolescent Psychiatry, 48(12), 1143–1154.
Bearss, K., Johnson, C., Smith, T., Lecavalier, L., Swiezy, N., Aman, M., … Scahill, L. (2015). Effect of parent training vs parent education on behavioral problems in children with autism spectrum disorder: A randomized clinical trial. JAMA, 313(15), 1524–1533. https://doi.org/10.1001/jama.2015.31502275445.
Blanchard-Fields, F., & Coats, A. H. (2008). The experience of anger and sadness in everyday problems impacts age differences in emotion regulation. Developmental Psychology, 44(6), 1547–1556.
Ducharme, J. M., Sanjuan, E., & Drain, T. (2007). Errorless compliance training: Success-focused behavioral treatment of children with asperger syndrome. Behavior Modification, 31(3), 329–344.
Fung, L. K., Mahajan, R., Nozzolillo, A., Bernal, P., Krasner, A., Jo, B., … Hardan, A. Y. (2016). Pharmacologic treatment of severe irritability and problem behaviors in autism: A systematic review and meta-analysis. Pediatrics, 137, S124-S135. https://doi.org/10.1542/peds.2015-2851K.
Gadow, K. D., DeVincent, C. J., & Drabick, D. A. G. (2008). Oppositional defiant disorder as a clinical phenotype in children with autism spectrum disorder. Journal of Autism and Developmental Disorders, 38(7), 1302–1310.
Hanley, G. P., Iwata, B. A., & McCord, B. E. (2003). Functional analysis of problem behavior: A review. Journal of Applied Behavior Analysis, 36(2), 147–185.
Johnson, C. R., Handen, B. L., Butter, E., Wagner, A., Mulick, J., Sukhodolsky, D. G., … Vitello, B. (2007). Development of a parent management training program for children with pervasive developmental disorders. Behavioral Interventions, 22, 201–221.
Kanne, S. M., & Mazurek, M. O. (2011). Aggression in children and adolescents with ASD: Prevalence and risk factors. Journal of Autism and Developmental Disorders, 41(7), 926–937.
Mayes, S. D., Calhoun, S. L., Aggarwal, R., Baker, C., Mathapati, S., Anderson, R., & Petersen, C. (2012). Explosive, oppositional, and aggressive behavior in children with autism compared to other clinical disorders and typical children. Research in Autism Spectrum Disorders, 6(1), 1–10.
Mayes, S. D., Kokotovich, C., Mathiowetz, C., Baweja, R., Calhoun, S. L., & Waxmonsky, J. (2017). Disruptive mood dysregulation disorder symptoms by age in autism, ADHD, and general population samples. Journal of Mental Health Research in Intellectual Disabilities, 10(4), 345–359. https://doi.org/10.1080/19315864.2017.1338804.
McDougle, C. J., Stigler, K. A., Erickson, C. A., & Posey, D. J. (2008). Atypical antipsychotics in children and adolescents with autistic and other pervasive developmental disorders. The Journal of Clinical Psychiatry, 69(Suppl 4), 15–20.
Patel, S., Day, T. N., Jones, N., & Mazefsky, C. A. (2017). Association between anger rumination and autism symptom severity, depression symptoms, aggression, and general dysregulation in adolescents with autism spectrum disorder. Autism, 21(2), 181–189. https://doi.org/10.1177/1362361316633566.
Postorino, V., Sharp, W. G., McCracken, C. E., Bearss, K., Burrell, T. L., Evans, A. N., & Scahill, L. (2017). A systematic review and meta-analysis of parent training for disruptive behavior in children with autism Spectrum disorder. [Review]. Clinical Child and Family Psychology Review, 20(4), 391–402. https://doi.org/10.1007/s10567-017-0237-2.
Potegal, M., Kosorok, M. R., & Davidson, R. J. (2003). Temper tantrums in young children: 2. Tantrum duration and temporal organization. Journal of Developmental and Behavioral Pediatrics, 24(3), 148–154.
Reese, R. M., Richman, D. M., Belmont, J. M., & Morse, P. (2005). Functional characteristics of disruptive behavior in developmentally disabled children with and without autism. Journal of Autism and Developmental Disorders, 35(4), 419–428.
RUPP Autism Network. (2005). Risperidone treatment of autistic disorder: Longer-term benefits and blinded discontinuation after 6 months. The American Journal of Psychiatry, 162(7), 1361–1369.
Shattuck, P. T., Seltzer, M. M., Greenberg, J. S., Orsmond, G. I., Bolt, D., Kring, S., … Lord, C. (2007). Change in autism symptoms and maladaptive behaviors in adolescents and adults with an autism spectrum disorder. Journal of Autism and Developmental Disorders, 37(9), 1735–1747.
Siegel, M., Milligan, B., Chemelski, B., Payne, D., Ellsworth, B., Harmon, J., … Smith, K. A. (2014). Specialized inpatient psychiatry for serious behavioral disturbance in autism and intellectual disability. Journal of Autism and Developmental Disorders, 44(12), 3026–3032. doi: https://doi.org/10.1007/s10803-014-2157-z.
Simonoff, E., Jones, C. R. G., Baird, G., Pickles, A., Happé, F., & Charman, T. (2013). The persistence and stability of psychiatric problems in adolescents with autism spectrum disorders. Journal of Child Psychology and Psychiatry, 54(2), 186–194.
Smith, T., Groen, A. D., & Wynn, J. W. (2000). Randomized trial of intensive early intervention for children with pervasive developmental disorder. American Journal of Mental Retardation, 105(4), 269–285.
Stringaris, A., Goodman, R., Ferdinando, S., Razdan, V., Muhrer, E., Leibenluft, E., & Brotman, M. A. (2012). The affective reactivity index: A concise irritability scale for clinical and research settings. Journal of Child Psychology and Psychiatry, 53, 1109. https://doi.org/10.1111/j.1469-7610.2012.02561.x.
Vismara, L. A., & Rogers, S. J. (2010). Behavioral treatments in autism spectrum disorder: What do we know? Annual Review of Clinical Psychology, 6, 447–468.
Volkmar, F., Siegel, M., Woodbury-Smith, M., King, B., McCracken, J., & State, M. (2014). Practice parameter for the assessment and treatment of children and adolescents with autism spectrum disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 53(2), 237–257. https://doi.org/10.1016/j.jaac.2013.10.013.
Williams, S. K., Scahill, L., Vitiello, B., Aman, M. G., Arnold, L. E., McDougle, C. J., … Sparrow, S. (2006). Risperidone and adaptive behavior in children with autism. Journal of the American Academy of Child and Adolescent Psychiatry, 45(4), 439.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer Science+Business Media LLC
About this entry
Cite this entry
Sukhodolsky, D.G., Gladstone, T.R., Marsh, C.L. (2018). Irritability in Autism. In: Volkmar, F. (eds) Encyclopedia of Autism Spectrum Disorders. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6435-8_102263-1
Download citation
DOI: https://doi.org/10.1007/978-1-4614-6435-8_102263-1
Received:
Accepted:
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4614-6435-8
Online ISBN: 978-1-4614-6435-8
eBook Packages: Springer Reference Behavioral Science and PsychologyReference Module Humanities and Social SciencesReference Module Business, Economics and Social Sciences