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Basal Ganglia: Dystonia

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Neuroscience in the 21st Century
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Abstract

Dystonia is a relatively common movement disorder and characterized by sustained or repetitive involuntary muscle contractions and abnormal postures. In this chapter, basal ganglia circuitry and recent electrophysiological findings in dystonia are briefly summarized, and pathophysiology of dystonia is discussed.

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Abbreviations

Cx:

Cerebral cortex

CL:

Central lateral nucleus

DA:

Dopamine

DBS:

Deep brain stimulation

GABA:

γ-Aminobutyric acid

GP:

Globus pallidus

GPe:

External segment of the globus pallidus

GPi:

Internal segment of the globus pallidus

PTD:

Primary torsion dystonia

SNc:

Substantia nigra pars compacta

SNr:

Substantia nigra pars reticulata

STN:

Subthalamic nucleus

Str:

Striatum

Th:

Thalamus

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Correspondence to Atsushi Nambu .

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© 2022 Springer Science+Business Media, LLC, part of Springer Nature

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Nambu, A., Chiken, S. (2022). Basal Ganglia: Dystonia. In: Pfaff, D.W., Volkow, N.D., Rubenstein, J. (eds) Neuroscience in the 21st Century. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6434-1_123-3

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  • DOI: https://doi.org/10.1007/978-1-4614-6434-1_123-3

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-6434-1

  • Online ISBN: 978-1-4614-6434-1

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

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