Encyclopedia of Metagenomics

Living Edition
| Editors: Karen E. Nelson

Early Gut Microbiome and Polymicrobial Infection

Living reference work entry
DOI: https://doi.org/10.1007/978-1-4614-6418-1_798-1



Microbiome: vast numbers of microorganisms in a given environment; in this entry, the gut of neonates.

Polymicrobial disease: several microorganisms implicated in the pathogenesis of disease.


The recent rise of “omic” technologies has led to an expansive lexicon of terms, suffixed by -ome. One such term, which is receiving more attention than most, is “microbiome.” The microbiome refers to the ecological community of commensal, symbiotic, and pathogenic microorganisms colonizing the human body. Although some controversy surrounds the original appearance of the term, Joshua Lederberg is generally accredited with the initial coinage (Lederberg and McCray 2001). This entry will focus on the importance of the microbiome in health and disease, specifically related to the temporal development of the bacterial community in the gut following birth.

Methods to Elucidate the Gut...


Bacterial Community Preterm Infant Short Bowel Syndrome Atopic Disease Necrotizing Enterocolitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.University of NorthumbriaNewcastle upon TyneUK