Synonyms
Definition
Functional gene arrays (FGAs) are a special type of microarray containing probes for key genes involved in microbial functional processes, such as biogeochemical cycling of carbon, nitrogen, sulfur, phosphorus, and metals, biodegradation of environmental contaminants, antibiotic resistance, energy processing, and stress response. GeoChips are considered to be the most comprehensive FGAs and an important metagenomic tool for microbial community analysis.
Introduction
Microorganisms are the most diverse group of organisms known in terms of phylogeny and functionality. However, they do not live alone but form distinct communities and play integrated and unique roles in ecosystems, such as biogeochemical cycling of carbon (C), nitrogen (N), sulfur (S), phosphorus (P), and metals (e.g., iron, copper, zinc), biodegradation or stabilization of environmental contaminants, and interaction with hosts. Therefore, one of the most...
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Acknowledgments
This work conducted by ENIGMA (Ecosystems and Networks Integrated with Genes and Molecular Assemblies) (http://enigma.lbl.gov), a Scientific Focus Area Program at Lawrence Berkeley National Laboratory, was supported by the Office of Science, Office of Biological and Environmental Research, of the US Department of Energy under Contract No. DE-AC02-05CH11231 and by the Oklahoma Applied Research Support (OARS), Oklahoma Center for the Advancement of Science and Technology (OCAST), State of Oklahoma, through AR11-035 and AR062-034.
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He, Z., Van Nostrand, J.D., Zhou, J.(. (2013). GeoChip-Based Metagenomic Technologies for Analyzing Microbial Community Functional Structure and Activities. In: Nelson, K. (eds) Encyclopedia of Metagenomics. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6418-1_760-4
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DOI: https://doi.org/10.1007/978-1-4614-6418-1_760-4
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