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Encyclopedia of Metagenomics pp 1–8Cite as

Microbial Infection, Leukemia and Lymphoma Associated with

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Introduction

Microbial infections by bacteria, viruses, fungi, and opportunistic pathogens are a common occurrence in leukemia and lymphoma and account for a large share of infections. They cause significant morbidity and mortality to their host. Each malignant disease harbors a unique set of infections, and the frequency of infection depends on the underlying neoplasm and state of the disease. Several predisposing factors such as state of disease, cytotoxicity induced by immunosuppressive medications, intensity and depth of neutropenia, defects in host humoral and cellular defense mechanisms, or immune system impairment can make a patient more susceptible to infection. The infectious agents are present as cofactors and at times as causative agents. Infections and the associated disease are many times endemic to particular geographical area(s). It is estimated that almost 80 % of acute leukemia patients and 70 % of lymphoma patients develop infection during their disease course...

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Authors and Affiliations

  1. University of Texas Medical Branch, Sealy Center on Aging, 301 University Blvd, Galveston, TX, 77555-0177, USA

    Preeti Zanwar

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  1. Preeti Zanwar
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Correspondence to Preeti Zanwar .

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Editors and Affiliations

  1. J. Craig Venter Institute (JCVI), Rockville, Maryland, USA

    Karen E. Nelson

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Zanwar, P. (2013). Microbial Infection, Leukemia and Lymphoma Associated with. In: Nelson, K. (eds) Encyclopedia of Metagenomics. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6418-1_60-4

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  • DOI: https://doi.org/10.1007/978-1-4614-6418-1_60-4

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  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-6418-1

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