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Encyclopedia of Metagenomics pp 1–4Cite as

Fecal Microbiome in Dogs with Acute Diarrhea and Idiopathic Inflammatory Bowel Disease

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Synonyms

Gastrointestinal Microbiota; IBD; Metagenomics; Microbiome

Definition

Characterization of changes in the fecal microbiome in dogs suffering from idiopathic inflammatory bowel disease (IBD) or acute hemorrhagic diarrhea (AHD).

Introduction

In dogs, chronic enteropathies (CE) describe a range of chronic diseases of the intestines regardless of etiology or pathogenesis. Idiopathic inflammatory bowel disease (IBD) is a subset of chronic enteropathies and is described as any condition associated with the presence of chronic (>3 weeks) gastrointestinal signs, inflammatory infiltration of the GI tract, and where a specific etiology cannot be identified (Simpson and Jergens 2011). Dogs with idiopathic IBD do not respond to dietary treatment approaches or antibiotic trials, and these dogs typically require immune-suppressive treatment.

Dogs may develop an acute onset of hemorrhagic diarrhea (AHD). There are several potential causes of AHD, including infectious organisms and/or their...

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References

  • Allenspach K, House A, Smith K, McNeill FM, Hendricks A, Elson-Riggins J, Riddle A, Steiner JM, Werling D, Garden OA, Catchpole B, Suchodolski JS. Evaluation of mucosal bacteria and histopathology, clinical disease activity and expression of Toll-like receptors in German shepherd dogs with chronic enteropathies. Vet Microbiol. 2010;146:326–35.

    Article  CAS  PubMed  Google Scholar 

  • Mansfield CS, James FE, Craven M, Davies DR, O’Hara AJ, Nicholls PK, Dogan B, Macdonough SP, Simpson KW. Remission of histiocytic ulcerative colitis in boxer dogs correlates with eradication of invasive intramucosal Escherichia coli. J Vet Intern Med. 2009;23:964–9.

    Article  CAS  PubMed  Google Scholar 

  • Markel MEB, Unterer SN, Oliveira-Barros LM, Grellet A, Allenspach K, Toresson L, Luckschander-Zeller N, Suchodolski JS. Characterization of fecal dysbiosis in dogs with chronic enteropathies and acute hemorrhagic diarrhea. J Vet Intern Med. 2012;26:765–6.

    Google Scholar 

  • Simpson KW, Jergens AE. Pitfalls and progress in the diagnosis and management of canine inflammatory bowel disease. Vet Clin North Am Small Anim Pract. 2011;41:381–98.

    Article  PubMed  Google Scholar 

  • Simpson KW, Dogan B, Rishniw M, Goldstein RE, Klaessig S, McDonough PL, German AJ, Yates RM, Russell DG, Johnson SE, Berg DE, Harel J, Bruant G, McDonough SP, Schukken YH. Adherent and invasive Escherichia coli is associated with granulomatous colitis in boxer dogs. Infect Immun. 2006;74:4778–92.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Suchodolski JS, Xenoulis PG, Paddock CG, Steiner JM, Jergens AE. Molecular analysis of the bacterial microbiota in duodenal biopsies from dogs with idiopathic inflammatory bowel disease. Vet Microbiol. 2010;142:394–400.

    Article  CAS  PubMed  Google Scholar 

  • Suchodolski JS, Dowd SE, Wilke V, Steiner JM, Jergens AE. 16S rRNA gene pyrosequencing reveals bacterial dysbiosis in the duodenum of dogs with idiopathic inflammatory bowel disease. Plos ONE. 2012a;7:e39333.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Suchodolski JS, Markel ME, Garcia-Mazcorro JF, Unterer S, Heilmann RM, Dowd SE, Kachroo P, Ivanov I, Minamoto Y, Dillman EM, Steiner JM, Cook AK, Toresson L. The fecal microbiome in dogs with acute diarrhea and idiopathic inflammatory bowel disease. Plos ONE. 2012b;7:e51907.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Unterer S, Strohmeyer K, Kruse BD, Sauter-Louis C, Hartmann K. Treatment of aseptic dogs with hemorrhagic gastroenteritis with amoxicillin/clavulanic acid: a prospective blinded study. J Vet Intern Med. 2011;25:973–9.

    Article  CAS  PubMed  Google Scholar 

  • Xenoulis PG, Palculict B, Allenspach K, Steiner JM, Van House AM, Suchodolski JS. Molecular-phylogenetic characterization of microbial communities imbalances in the small intestine of dogs with inflammatory bowel disease. FEMS Microbiol Ecol. 2008;66:579–89.

    Article  CAS  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Gastrointestinal Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, 4474 TAMU, College Station, TX, 77843-4474, USA

    Jan S. Suchodolski

Authors
  1. Jan S. Suchodolski
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Corresponding author

Correspondence to Jan S. Suchodolski .

Editor information

Editors and Affiliations

  1. J. Craig Venter Institute (JCVI), Rockville, Maryland, USA

    Karen E. Nelson

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© 2013 Springer Science+Business Media New York

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Suchodolski, J.S. (2013). Fecal Microbiome in Dogs with Acute Diarrhea and Idiopathic Inflammatory Bowel Disease. In: Nelson, K. (eds) Encyclopedia of Metagenomics. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6418-1_433-1

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  • DOI: https://doi.org/10.1007/978-1-4614-6418-1_433-1

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  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-6418-1

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