SILVA (from Latin silva, forest) is a comprehensive web resource (http://www.arb-silva.de) for up-to-date, quality-controlled databases of aligned ribosomal RNA gene (rDNA) sequences from the Bacteria, Archaea, and Eukarya domains.
Sequencing the ribosomal RNA gene (rDNA) is the method of choice for nucleic acid-based detection and identification of microbes, their taxonomic assignment, phylogenetic analysis, and investigation of microbial diversity. Today (July 2012), more than 3.5 million small and large subunit (SSU and LSU) rDNA sequences are publicly available and their analysis demands for appropriate software tools and specialized, quality-controlled databases. The SILVA datasets, established in 2007, provide high-quality, comprehensive rDNA datasets comprising sequences from the Bacteria, Archaea, and Eukarya domains.cxAll...
KeywordsManifold Assure Microbe Archaea
- Altschul S, Madden T, et al. BLAST and PSI-BLAST: a new generation of protein database search programs. FASEB J. 1998;12:A1326.Google Scholar
- Garrity GM, Bell JA, et al. Taxonomic outline of the prokaryotes. Bergey’s manual of systematic bacteriology. 2nd ed. New York: Springer; 2004. Release 5.0.Google Scholar