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Transgenic Livestock , Decreasing Environmental Impact of

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Sustainable Food Production

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Abbreviations

Arabinoxylan:

A polymeric backbone of β(1,4) linked xylose residues with attached C(O)-2,3-linked arabinose residues that is found mainly in cereal grains. It becomes highly viscous when dissolved in the gastrointestinal tract and is not digested by monogastric animals.

Eutrophication:

A process where water bodies receive excess nutrients especially as phosphorus or nitrogen that stimulate excessive plant and algal growth resulting in reduced water quality.

β-Glucan:

A polymer found primarily in cereal grains consisting of β (1,3:1,4) linked glucose residues that becomes viscous on solubilization in the gastrointestinal tract and is not digested by monogastric animals.

Glycanase:

Any enzyme that catalyzes the hydrolysis of a glycan, which includes glucanases and xylanases of all types.

Phytase:

Any type of phosphatase enzyme that catalyzes the hydrolysis of phytic acid releasing phosphate molecules.

Phytic Acid:

Inositol hexakisphosphate (or phytate when in the salt form) is the principle storage form of phosphorus in many plants. It accounts for 50–80% of the total phosphorus present and is poorly digested by monogastric animals.

Bibliography

  1. Adams NR, Briegel JR, Ward KA (2002) The impact of a transgene for ovine growth hormone on the performance of two breeds of sheep. J Anim Sci 80:2325–2333

    PubMed  CAS  Google Scholar 

  2. Bai Y, Wang J, Zhang Z, Shi P, Luo H, Huang H, Feng Y, Yao B (2010a) Extremely acidic β−1,4-glucanase, CelA4, from thermoacidophilic Alicyclobacillus sp. A4 with high protease resistance and potential as a pig feed additive. J Agric Food Chem 58:1970–1975

    PubMed  CAS  Google Scholar 

  3. Bai Y, Wang J, Zhang Z, Shi P, Luo H, Huang H, Luo C, Yao B (2010b) Expression of an extremely acidic β-1,4-glucanase from thermoacidophilic Alicyclobacillus sp. A4 in Pichia pastoris is improved by truncating the gene sequence. Microb Cell Fact 9:33

    PubMed  Google Scholar 

  4. Barkema HW, Green MJ, Bradley AJ, Zadoks RN (2009) Invited review: the role of contagious disease in udder health. J Dairy Sci 92:4717–4729

    PubMed  CAS  Google Scholar 

  5. Beauchemin KA, Colombatto D, Morgavi DP (2004a) A rationale for the development of feed enzyme products for ruminants. Can J Anim Sci 84:23–36

    CAS  Google Scholar 

  6. Beauchemin KA, Colombatto D, Morgavi DP, Yang WZ, Rode LM (2004b) Mode of action of exogenous cell wall degrading enzymes for ruminants. Can J Anim Sci 84:13–22

    CAS  Google Scholar 

  7. Brown WRA, Lee NCO, Xu Z, Smith MCM (2011) Serine recombinases as tools for genome engineering. Methods 53:372–379

    PubMed  CAS  Google Scholar 

  8. Bulger M, Groudine M (2010) Enhancers: the abundance and function of regulatory sequences beyond promoters. Dev Biol 339:250–257

    PubMed  CAS  Google Scholar 

  9. Cannarrozzi G, Schraudolph NN, Faty M, von Rohr RP, Friberg MT, Roth AC, Gonnet P, Gonnet G, Barral Y (2010) A role for codon order in translation dynamics. Cell 141:355–367

    PubMed  CAS  Google Scholar 

  10. Carew R (2010) Ammonia emissions from livestock industries in Canada: feasibility of abatement strategies. Environ Pollut 158:2618–2626

    PubMed  CAS  Google Scholar 

  11. Cheung QC, Turner PV, Song C, Wu D, Cai HY, Macinnes JI, Li J (2008) Enhanced resistance to bacterial infection in protegrin-1 transgenic mice. Antimicrob Agents Chemother 52:1812–1819

    PubMed  CAS  Google Scholar 

  12. Cho J, Choi K, Darden T, Reynolds PR, Petitte JN, Shears SB (2006) Avian multiple inositol polyphosphate phosphatase is an active phytase that can be engineered to help ameliorate the planet’s “phosphate crisis”. J Biotechnol 126:248–259

    PubMed  CAS  Google Scholar 

  13. Clemens ET, Stevens CE, Southworth M (1975) Sites of organic acid production and pattern of digesta movement in the gastrointestinal tract of swine. J Nutr 105:759–768

    PubMed  CAS  Google Scholar 

  14. Clements JE, Wall RJ, Narayan O, Hauer D, Schoborg R, Sheffer D, Powell A, Carruth LM, Zink MC, Rexroad CE (1994) Development of transgenic sheep that express the Visna virus envelope gene. Virology 200:370–380

    PubMed  CAS  Google Scholar 

  15. CODEX 2008 Report of the seventh session of the CodexAd Hoc intergovernmental task force on foods derived from biotechnology. http://www.codexalimentarius. net/web/archives.jsp?year = 08

  16. Cordell D, Drangert JO, White S (2009) The story of phosphorus: global food security and food for thought. Glob Environ Change 19:292–305

    Google Scholar 

  17. Cowieson AJ, Bedford MR, Selle PH, Ravindran V (2009) Phytate and microbial phytase: implications for endogenous nitrogen losses and nutrient availability. World’s Poult Sci J 65:401–417

    Google Scholar 

  18. Cowieson AJ, Bedford MR, Ravindran V (2010) Interactions between xylanase and glucanase in maize-soy-based diets for broilers. Brit Poult Sci 51:246–257

    CAS  Google Scholar 

  19. Dahlke F, Ribeiro AML, Kessler AM, Lima AR, Maiorka A (2003) Effects of corn particle size and physical form of the diet on the gastrointestinal structures of broiler chickens. Braz J Poult Sci 5:61–67

    Google Scholar 

  20. D'Apice AJ, Cowan PJ (2008) Gene-modified pigs. Xenotransplantation 15:87–90

    PubMed  Google Scholar 

  21. Denning C, Burl S, Ainslie A, Bracken J, Dinnyes A, Fletcher J, King T, Ritchie M, Ritchie WA, Rollo M, de Sousa P, Travers A, Wilmut I, Clark AJ (2001) Deletion of the α(1,3)galactosyl transferase (GGTA1) gene and the prion protein (PrP) gene in sheep. Nat Biotechnol 19:559–562

    PubMed  CAS  Google Scholar 

  22. Devlin RH, Sakhrani D, Tymchuk WE, Rise ML, Goh B (2009) Domestication and growth hormone transgenesis cause similar changes in gene expression in coho salmon (Oncorhynchus kisutch). Proc Natl Acad Sci USA 106:3047–3052

    PubMed  CAS  Google Scholar 

  23. Fan CL, Han XY, Xu ZR, Wang LJ, Shi LR (2009) Effects of β-glucanase and xylanase supplementation on gastrointestinal digestive enzyme activities of weaned piglets fed a barley-based diet. J Anim Physiol Anim Nutr 93:271–276

    CAS  Google Scholar 

  24. Fan Z, Wagschal K, Lee CC, Kong Q, Shen KA, Maiti IB, Yuan L (2009) The construction and characterization of two xylan-degrading chimeric enzymes. Biotechnol Bioeng 102:684–692

    PubMed  CAS  Google Scholar 

  25. Fang J, Qian JJ, Yi S, Harding TC, Tu GH, VanRoey M, Jooss K (2005) Stable antibody expression at therapeutic levels using the 2A peptide. Nat Biotechnol 23:584–590

    PubMed  CAS  Google Scholar 

  26. Food and Agriculture Organization (2006) World agriculture: towards 2030/2050-interim report. Food and Agriculture Organization, Rome

    Google Scholar 

  27. Food and Agriculture Organization (2009) State of food and agriculture – Livestock in the balance. Food and Agriculture Organization, Rome

    Google Scholar 

  28. Fredrick K, Ibba M (2010) How the sequence of a gene can tune its translation. Cell 141:227–229

    PubMed  CAS  Google Scholar 

  29. Garner DL (2006) Flow cytometric sexing of mammalian sperm. Theriogenology 65:943–957

    PubMed  Google Scholar 

  30. Gerber PJ, Vellinga TV, Steinfeld H (2010) Issues and options in addressing the environmental consequences of livestock sector's growth. Meat Sci 84:244–247

    PubMed  CAS  Google Scholar 

  31. Golovan S, Wang G, Zhang J, Forsberg CW (2000) Characterization and overproduction of the Escherichia coli appA encoded bifunctional enzyme which exhibits both phytase and acid phosphatase activities. Can J Microbiol 46:59–71

    PubMed  CAS  Google Scholar 

  32. Golovan SP, Hayes MA, Phillips JP, Forsberg CW (2001) Transgenic mice expressing bacterial phytase as a model for phosphorus pollution control. Nat Biotechnol 19:429–433

    PubMed  CAS  Google Scholar 

  33. Golovan SP, Meidinger RG, Ajakaiye A, Cottrill M, Wiederkehr MZ, Barney D, Plante C, Pollard J, Fan MZ, Hayes MA, Laursen J, Hjorth JP, Hacker RR, Phillips JP, Forsberg CW (2001) Pigs expressing salivary phytase produce low phosphorus manure. Nat Biotechnol 19:741–745

    PubMed  CAS  Google Scholar 

  34. Guinotte F, Gautron J, Soumarmon A, Robert JC, Peranzi G, Nys Y (1993) Gastric acid secretion in the chicken: effect of histamine H2 antagonists and H+/K(+)-ATPase inhibitors on gastro-intestinal pH and of sexual maturity calcium carbonate level and particle size on proventricular H+/K + ATPase activity. Comp Biochem Physiol Comp Physiol 106:319–327

    PubMed  CAS  Google Scholar 

  35. Hall J, Ali S, Surani MA, Hazlewood GP, Clark AJ, Simons JP, Hirst BH, Gilbert HJ (1993) Manipulation of the repertoire of digestive enzymes secreted into the gastrointestinal tract of transgenic mice. Nat Biotechnol 11:376–379

    CAS  Google Scholar 

  36. Hess M, Sczyrba A, Egan R, Kim TW, Chokhawala H, Schroth G, Luo S, Clark DS, Chen F, Zhang T, Mackie RI, Pennacchio LA, Tringe SG, Visel A, Woyke T, Wang Z, Rubin EM (2011) Metagenomic discovery of biomass-degrading genes and genomes from cow rumen. Science 331:463–467

    PubMed  CAS  Google Scholar 

  37. Huang H, Zhang R, Fu D, Luo J, Li Z, Luo H, Shi P, Yang P, Diao Q, Yao B (2011) Diversity, abundance and characterization of ruminal cysteine phytases suggest their important role in phytate degradation. Environ Microbiol 13:747–757

    PubMed  CAS  Google Scholar 

  38. Jackson KA, Berg JM, Murray JD, Maga EA (2010) Evaluating the fitness of human lysozyme transgenic dairy goats: growth and reproductive traits. Transgenic Res 19:977–986

    PubMed  CAS  Google Scholar 

  39. Jerrett SA, Goodge WR (1973) Evidence for amylase in avian salivary glands. J Morphol 139:27–45

    PubMed  CAS  Google Scholar 

  40. Ji F, Casper DP, Brown PK, Spangler DA, Haydon KD, Pettigrew JE (2008) Effects of dietary supplementation of an enzyme blend on the ileal and fecal digestibility of nutrients in growing pigs. J Anim Sci 86:1533–1543

    PubMed  CAS  Google Scholar 

  41. Keita D, Heath L, Albina E (2010) Control of African swine fever virus replication by small interfering RNA targeting the A151R and VP72 genes. Antivir Ther 15:727–736

    PubMed  CAS  Google Scholar 

  42. Kellogg RL, Lander CH, Moffitt DC, Gollehon N (2000) Manure nutrients relative to the capacity of cropland and pastureland to assimilate nutrients: spatial and temporal trends for the United States. http://www.nrcs. usda. gov/technical/NRI/pubs/manntr. html 1–140

  43. Knowlton KF, Taylor MS, Hill SR, Cobb C, Wilson KF (2007) Manure nutrient excretion by lactating cows fed exogenous phytase and cellulase. J Dairy Sci 90:4356–4360

    PubMed  CAS  Google Scholar 

  44. Leahy SC, Kelly WJ, Altermann E, Ronimus RS, Yeoman CJ, Pacheco DM, Li D, Kong Z, McTavish S, Sang C, Lambie SC, Janssen PH, Dey D, Attwood GT (2010) The genome sequence of the rumen methanogen Methanobrevibacter ruminantium reveals new possibilities for controlling ruminant methane emissions. PLoS One 5:e8926

    PubMed  Google Scholar 

  45. Levasseur A, Asther M, Record E (2005) Overproduction and characterization of xylanase B from Asperguillus niger. Can J Microbiol 51:177–183

    PubMed  CAS  Google Scholar 

  46. Lo D, Pursel V, Linton PJ, Sandgren E, Behringer R, Rexroad C, Palmiter RD, Brinster RL (1991) Expression of mouse IgA by transgenic mice, pigs and sheep. Eur J Immunol 21:1001–1006

    PubMed  CAS  Google Scholar 

  47. Long CR, Tessanne KJ, Golding MC (2010) Applications of RNA interference-based gene silencing in animal agriculture. Reprod Fertil Dev 22:47–58

    PubMed  CAS  Google Scholar 

  48. Luo H, Yang J, Yang P, Li J, Huang H, Shi P, Bai Y, Wang Y, Fan Y, Yao B (2010) Gene cloning and expression of a new acidic family 7 endo-β-1,3-1,4-glucanase from the acidophilic fungus Bispora sp. MEY-1. Appl Microbiol Biotechnol 85:1015–1023

    PubMed  CAS  Google Scholar 

  49. Lyall J, Irvine RM, Sherman A, McKinley TJ, Néñz A, Purdie A, Outtrim L, Brown IH, Rolleston-Smith G, Sang H, Tiley L (2011) Suppression of Avian influenza transmission in genetically modified chickens. Science 331:223–226

    PubMed  CAS  Google Scholar 

  50. Maenz DD, Classen HL (1998) Phytase activity in the small intestinal brush border membrane of the chicken. Poult Sci 77:557–563

    PubMed  CAS  Google Scholar 

  51. Maga EA, Cullor JS, Smith W, Anderson GB, Murray JD (2006) Human lysozyme expressed in the mammary gland of transgenic dairy goats can inhibit the growth of bacteria that cause mastitis and the cold-spoilage of milk. Foodborne Pathog Dis 3:384–392

    PubMed  CAS  Google Scholar 

  52. Martinez-Salas E (1999) Internal ribosome entry site biology and its use in expression vectors. Curr Opin Biotechnol 10:458–464

    PubMed  CAS  Google Scholar 

  53. Muller M, Brem G (1994) Transgenic strategies to increase disease resistance in livestock. Reprod Fertil Dev 6:605–613

    PubMed  CAS  Google Scholar 

  54. Naqvi S, Farre G, Sanahuja G, Capell T, Zhu C, Christou P (2010) When more is better: multigene engineering in plants. Trends Plant Sci 15:48–56

    PubMed  CAS  Google Scholar 

  55. Noble MS, Rodriguez-Zas S, Cook JB, Bleck GT, Hurley WL, Wheeler MB (2002) Lactational performance of first-parity transgenic gilts expressing bovine α-lactalbumin in their milk. J Anim Sci 80:1090–1096

    PubMed  CAS  Google Scholar 

  56. Notter DR (1999) The importance of genetic diversity in livestock populations of the future. J Anim Sci 77:61–69

    PubMed  CAS  Google Scholar 

  57. Nottle MB, Nagashima H, Verma PJ, Du ZT, Grupen CG, McIlfatrick SM, Ashman RJ, Harding MP, Giannakis C, Wigley PL, Lyons IG, Harrison DT, Luxford BG, Campbell RG, Crawford RJ, Robins AJ (1999) Production and analysis of transgenic pigs containing a metallothionein porcine growth hormone gene construct. In: Transgenic animals in agriculture. Commonwealth Agriculture Bureau International, London, pp 145–156

    Google Scholar 

  58. NRC (1998) Nutrient requirements of swine. National Academy Press, Washington, DC

    Google Scholar 

  59. Nyachoti CM, Arntfield SD, Guenter W, Cenkowski S, Opapeju FO (2006) Effect of micronized pea and enzyme supplementation on nutrient utilization and manure output in growing pigs. J Anim Sci 84:2150–2156

    PubMed  CAS  Google Scholar 

  60. Ohnishi H, Samuelson LC, Yule DI, Ernst SA, Williams JA (1997) Overexpression of Rab3D enhances regulated amylase secretion from pancreatic acini of transgenic mice. J Clin Invest 100:3044–3052

    PubMed  CAS  Google Scholar 

  61. Olmedo LA, Samar ME, Avila RE, de Crosa MG, Dettin L (2000) Avian minor salivary glands: an ultrastructural study of the secretory granules in mucous and seromucous cells. Acta Odontol Latinoam 13:87–99

    PubMed  CAS  Google Scholar 

  62. Peters A, Lebzien P, Meyer U, Borchert U, Bulang M, Flachowsky G (2010) Effect of exogenous fibrolytic enzymes on ruminal fermentation and nutrient digestion in dairy cows. Arch Anim Nutr 64:221–237

    PubMed  CAS  Google Scholar 

  63. Pursel VG, Pinkert CA, Miller KF, Bolt DJ, Campbell RG, Palmiter RD, Brinster RL, Hammer RE (1989) Genetic engineering of livestock. Science 244:1281–1287

    PubMed  CAS  Google Scholar 

  64. Pursel VG, Wall RJ, Michell AD, Elsasser TH, Solomon MB, Coleman ME, DeMayo F, Schwartz RJ (1999) Transgenic animals in agriculture. In: Expression of insulin-like growth factor-1 in skeletal muscle of transgenic swine. CABI Publishing, New York, pp 131–144

    Google Scholar 

  65. Pursel VG, Mitchell AD, Bee G, Elsasser TH, McMurtry JP, Wall RJ, Coleman ME, Schwartz RJ (2004) Growth and tissue accretion rates of swine expressing an insulin-like growth factor I transgene. Anim Biotechnol 15:33–45

    PubMed  CAS  Google Scholar 

  66. Rajan GH, Morris CA, Carruthers VR, Wilkins RJ, Wheeler TT (1996) The relative abundance of a salivary protein, bSP30, is correlated with susceptibility to bloat in cattle herds selected for high or low bloat susceptibility. Anim Genet 27:407–414

    PubMed  CAS  Google Scholar 

  67. Rao DECS, Rao KV, Reddy TP, Reddy VD (2009) Molecular characterization, physicochemical properties, known and potential applications of phytases: an overview. Crit Rev Biotechnol 29:182–198

    PubMed  CAS  Google Scholar 

  68. Rath D, Johnson LA (2008) Application and commercialization of flow cytometrically sex-sorted semen. Reprod Domest Anim 43(Suppl 2):338–346

    PubMed  Google Scholar 

  69. Rath D, Ruiz S, Sieg B (2003) Birth of female piglets following intrauterine insemination of a sow using flow cytometrically sexed boar semen. Vet Rec 152:400–401

    PubMed  CAS  Google Scholar 

  70. Reddy VA, Venu K, Rao DE, Rao KV, Reddy VD (2009) Chimeric gene construct coding for bi-functional enzyme endowed with endoglucanase and phytase activities. Arch Microbiol 191:171–175

    PubMed  CAS  Google Scholar 

  71. Rees WD, Hay SM (1995) The biosynthesis of threonine by mammalian cells: expression of a complete bacterial biosynthetic pathway in an animal cell. Biochem J 309(Pt 3):999–1007

    PubMed  CAS  Google Scholar 

  72. Rich KM, Perry BD (2010) The economic and poverty impacts of animal diseases in developing countries: New roles, new demands for economics and epidemiology. Prev Vet Med 97:1–8

    Google Scholar 

  73. Richt JA, Kasinathan P, Hamir AN, Castilla J, Sathiyaseelan T, Vargas F, Sathiyaseelan J, Wu H, Matsushita H, Koster J, Kato S, Ishida I, Soto C, Robl JM, Kuroiwa Y (2007) Production of cattle lacking prion protein. Nat Biotechnol 25:132–138

    PubMed  CAS  Google Scholar 

  74. Romano PR, Wang J, O'Keefe RJ, Puzas JE, Rosier RN, Reynolds PR (1998) HiPER1, a phosphatase of the endoplasmic reticulum with a role in chondrocyte maturation. J Cell Sci 111:803–813

    PubMed  CAS  Google Scholar 

  75. Samar ME, Avila RE, Esteban FJ, Olmedo L, Dettin L, Massone A, Pedrosa JA, Peinado MA (2002) Histochemical and ultrastructural study of the chicken salivary palatine glands. Acta Histochem 104:199–207

    PubMed  Google Scholar 

  76. Schröder JJ, Smit AL, Cordell D, Rosemarin A (2011) Improved phosphorus use efficiency in agriculture: a key requirement for its sustainable use. Chemosphere 84(6):822–831

    PubMed  Google Scholar 

  77. Seo HW, Kim TM, Choi JW, Han BK, Song G, Han JY (2010) Evaluation of combinatorial cis-regulatory elements for stable gene expression in chicken cells. BMC Biotechnol 10:69

    PubMed  Google Scholar 

  78. Shi P, Tian J, Yuan T, Liu X, Huang H, Bai Y, Yang P, Chen X, Wu N, Yao B (2010) Paenibacillus sp. strain E18 bifunctional xylanase-glucanase with a single catalytic domain. Appl Environ Microbiol 76:3620–3624

    PubMed  CAS  Google Scholar 

  79. Simojoki H, Orro T, Taponen S, Pyorala S (2009) Host response in bovine mastitis experimentally induced with Staphylococcus chromogenes. Vet Microbiol 134:95–99

    PubMed  CAS  Google Scholar 

  80. Simojoki H, Hyvonen P, Orro T, Pyorala S (2010) High concentration of human lactoferrin in milk of rhLf-transgenic cows relieves signs of bovine experimental Staphylococcus chromogenes intramammary infection. Vet Immunol Immunopathol 136:265–271

    PubMed  CAS  Google Scholar 

  81. Skinner JT, Bauer S, Young V, Pauling G, Wilson J (2010) An economic analysis of the impact of subclinical (mild) necrotic enteritis in broiler chickens. Avian Dis 54:1237–1240

    PubMed  Google Scholar 

  82. Smith TC, Harper AL, Nair R, Wardyn SE, Hanson BM, Ferguson DD, Dressler AE (2011) Emerging swine zoonoses. Vector Borne Zoonotic Dis 11:1–10

    Google Scholar 

  83. Steinfeld H, Gerber P (2010) Livestock production and the global environment: consume less or produce better? Proc Natl Acad Sci USA 107:18237–18238

    PubMed  CAS  Google Scholar 

  84. Steinfeld H, Gerber P, Wassenaar T, Castel V, Rosales M, de Hann C (2006) Livestock’s long shadow – Evnironmental issues and options. FAO, Rome

    Google Scholar 

  85. Suzuki M, Fujimoto W, Goto M, Morimatsu M, Syuto B, Iwanaga T (2002) Cellular expression of gut chitinase mRNA in the gastrointestinal tract of mice and chickens. J Histochem Cytochem 50:1081–1089

    PubMed  CAS  Google Scholar 

  86. Szymczak AL, Workman CJ, Wang Y, Vignali KM, Dilioglou S, Vanin EF, Vignali DA (2004) Correction of multi-gene deficiency in vivo using a single ‘self-cleaving’ 2A peptide-based retroviral vector. Nat Biotechnol 22:589–594

    PubMed  CAS  Google Scholar 

  87. Tilman D, Fargione J, Wolff B, D'Antonio C, Dobson A, Howarth R, Schindler D, Schlesinger WH, Simberloff D, Swackhamer D (2001) Forecasting agriculturally driven global environmental changes. Science 292:281–284

    PubMed  CAS  Google Scholar 

  88. Wall RJ, Powell AM, Paape MJ, Kerr DE, Bannerman DD, Pursel VG, Wells K, Talbot N, Hawk HW (2005) Genetically enhanced cows resist intramammary Staphylococcus aureus infection. Nat Biotechnol 23:445–451

    PubMed  CAS  Google Scholar 

  89. Wen TN, Chen JL, Lee SH, Yang NS, Shyur LF (2005) A truncated Fibrobacter succinogenes 1,3-1,4-β-D-glucanase with improved enzymatic activity and thermotolerance. Biochemistry 44:9197–9205

    PubMed  CAS  Google Scholar 

  90. Wheeler MB, Bleck GT, Donovan SM (2001) Transgenic alteration of sow milk to improve piglet growth and health. Reprod Suppl 58:313–324

    PubMed  CAS  Google Scholar 

  91. Wheeler TT, Hood K, Oden K, McCracken J, Morris CA (2003) Bovine parotid secretory protein: structure, expression and relatedness to other BPI (bactericidal/permeability-increasing protein)-like proteins. Biochem Soc Trans 31:781–784

    PubMed  CAS  Google Scholar 

  92. Wise TG, Schafer DS, Lowenthal JW, Doran TJ (2008) The use of RNAi and transgenics to develop viral disease resistant livestock. Dev Biol (Basel) 132:377–382

    CAS  Google Scholar 

  93. Xue GP, Denman SE, Glassop D, Johnson JS, Dierens LM, Gobius KS, Aylward JH (1995) Modification of a xylanase cDNA isolated from an anaerobic fungus Neocallimastix patriciarum for high-level expression in Escherichia coli. J Biotechnol 38:269–277

    PubMed  CAS  Google Scholar 

  94. Yang W-J, Matsuda Y, Sano S, Masutani H, Nakagawa H (1991) Purification and characterization of phytase from rat intestinal mucosa. Biochim Biophys Acta 1075:75–82

    PubMed  CAS  Google Scholar 

  95. Yin HF, Fan BL, Yang B, Liu YF, Luo J, Tian XH, Li N (2006) Cloning of pig parotid secretory protein gene upstream promoter and the establishment of a transgenic mouse model expressing bacterial phytase for agricultural phosphorus pollution control. J Anim Sci 84:513–519

    PubMed  CAS  Google Scholar 

  96. Zhang JX, Meidinger R, Forsberg CW, Krell PJ, Phillips JP (1999) Expression and processing of a bacterial endoglucanase in transgenic mice. Arch Biochem Biophys 367:317–321

    PubMed  CAS  Google Scholar 

  97. Zhang F, Shi P, Bai Y, Luo H, Yuan T, Huang H, Yang P, Miao L, Yao B (2011) An acid and highly thermostable xylanase from Phialophora sp. G5. Appl Microbiol Biotechnol 89:1851–1858

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Animal and Food Science, University of Delaware, Newark, DE, 19716-2150, USA

    Dr. Serguei P. Golovan

  2. Department of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada

    Dr. Cecil W. Forsberg

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  1. Dr. Serguei P. Golovan
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  2. Dr. Cecil W. Forsberg
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Correspondence to Serguei P. Golovan .

Editor information

Editors and Affiliations

  1. Department de Produccio Vegetal i Ciencia Forestal, Universitat de Lleida/ICREA, Lleida, Spain

    Paul Christou

  2. Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain

    Paul Christou

  3. Department of Crop and Forest Sciences, University of Lleida, Lleida, Spain

    Roxana Savin

  4. University of New England, Marine Science Center, Biddeford, ME, USA

    Barry A. Costa-Pierce

  5. Department of Animal and Dairy Science Breeding and Genetics, University of Georgia, Athens, GA, USA

    Ignacy Misztal

  6. The Roslin Institute and Royal (Dick) School of Veterinary Studies, Division of Developmental Biology, University of Edinburgh, Midlothian, Scotland, UK

    C. Bruce A. Whitelaw

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Golovan, S.P., Forsberg, C.W. (2013). Transgenic Livestock , Decreasing Environmental Impact of. In: Christou, P., Savin, R., Costa-Pierce, B.A., Misztal, I., Whitelaw, C.B.A. (eds) Sustainable Food Production. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-5797-8_9

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