Skip to main content
SpringerLink
Log in
Book cover

Comprehensive Guide to Autism pp 387–409Cite as

PDD Behavior Inventories: Clinical and Research Applications to ASD

  • Reference work entry

  • 387 Accesses

Abstract

This chapter describes the PDD Behavior Inventory (PDDBI) and PDD Behavior Inventory-Screening Version (PDDBI-SV) which are relatively new informant-based rating scales useful clinically and for research studies. The information gathered from the PDDBI is unique in that it provides dimensional assessment of both problem behaviors and adaptive skills. Further, the scores that are derived are standardized on children with autism spectrum disorder (ASD) and take age into account. This enables the clinician or researcher to ascertain, for an individual case, whether scores are typical or atypically low or high for a child with ASD thereby facilitating identification of possible comorbid problems. The clinical applicability of the PDDBI and the importance of the behavior profiles revealed by this assessment instrument are described first using four case vignettes. This is followed by description of the role of the PDDBI in research using, as an example, a study which identified clinical subtypes of boys with ASD based on their and their mother’s monoamine oxidase A (MAOA) genotype. Finally, the new PDDBI-SV, a rapid screening tool for ASD which was published in 2011, is described along with issues involved in screening rare disorders. It was concluded that the PDDBI and PDDBI-SV are assessment tools that provide important information not usually found with other measures.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   1,199.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD   1,299.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  • Adams JB, Audhya T, McDonough-Means S, et al. Nutritional and metabolic status of children with autism vs. neurotypical children, and the association with autism severity. Nutr Metab (Lond). 2011;8(1):34.

    Article  Google Scholar 

  • Allen DA. Autistic spectrum disorders: clinical presentation in preschool children. J Child Neurol. 1988;3(Suppl):S48–56.

    Article  PubMed  Google Scholar 

  • American Psychiatric Association. Diagnostic and statistical manual of mental disorders. Fourth edition text revision. Washington, DC; 2000.

    Google Scholar 

  • Autism and Developmental Disabilities Monitoring Network, United States. Prevalence of autism spectrum disorders, 2006. MMWR Surveill Summ. 2009;58(10):1–20.

    Google Scholar 

  • Bent S, Bertoglio K, Ashwood P, Nemeth E, Hendren RL. Brief report: hyperbaric oxygen therapy (HBOT) in children with autism spectrum disorder: a clinical trial. J Autism Dev Disord. 2012;42(6):1127–32.

    Article  PubMed  Google Scholar 

  • Brunner HG, Nelen M, Breakefield XO, Ropers HH, van Oost BA. Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A. Science. 1993;262(5133):578–80.

    Article  PubMed  Google Scholar 

  • Buckholtz JW, Meyer-Lindenberg A. MAOA and the neurogenetic architecture of human aggression. Trends Neurosci. 2008;31(3):120–9.

    Article  PubMed  Google Scholar 

  • Caspi A, McClay J, Moffitt TE, et al. Role of genotype in the cycle of violence in maltreated children. Science. 2002;297(5582):851–4.

    Article  PubMed  Google Scholar 

  • Cerasa A, Gioia MC, Fera F, et al. Ventro-lateral prefrontal activity during working memory is modulated by MAO A genetic variation. Brain Res. 2008;1201:114–21.

    Article  PubMed  Google Scholar 

  • Chauhan A, Chauhan V, Brown WT, Cohen IL. Oxidative stress in autism: increased lipid peroxidation and reduced serum levels of ceruloplasmin and transferrin – the antioxidant proteins. Life Sci. 2004;75:2539–49.

    Article  PubMed  Google Scholar 

  • Cohen IL. Criterion-related validity of the PDD behavior inventory. J Autism Dev Disord. 2003;33(1):47–53.

    Article  PubMed  Google Scholar 

  • Cohen IL. PDD behavior inventory screening version professional manual. Lutz: Psychological Assessment Resources; 2011.

    Google Scholar 

  • Cohen IL, Sudhalter V. The PDD behavior inventory. Lutz: Psychological Assessment Resources; 2005a.

    Google Scholar 

  • Cohen IL, Sudhalter V. PDD behavior inventory professional manual. Lutz: Psychological Assessment Resources; 2005b.

    Google Scholar 

  • Cohen IL, Tsiouris J. Maternal recurrent mood disorders and high-functioning autism. J Autism Dev Disord. 2006;36:1077–8.

    Article  PubMed  Google Scholar 

  • Cohen IL, Fisch GS, Sudhalter V, et al. Social gaze, social avoidance, and repetitive behavior in fragile X males: a controlled study. Am J Ment Retard. 1988;92(5):436–46.

    PubMed  Google Scholar 

  • Cohen IL, Brown WT, Jenkins EC, et al. Fragile X syndrome in females with autism. Am J Med Genet. 1989a;34(2):302–3.

    Article  PubMed  Google Scholar 

  • Cohen IL, Vietze PM, Sudhalter V, Jenkins EC, Brown WT. Parent-child dyadic gaze patterns in fragile X males and in non-fragile X males with autistic disorder. J Child Psychol Psychiatry. 1989b;30(6):845–56.

    Article  PubMed  Google Scholar 

  • Cohen IL, Sudhalter V, Pfadt A, Jenkins EC, Brown WT, Vietze PM. Why are autism and the fragile-X syndrome associated? Conceptual and methodological issues. Am J Hum Genet. 1991a;48(2):195–202.

    PubMed  Google Scholar 

  • Cohen IL, Vietze PM, Sudhalter V, Jenkins EC, Brown WT. Effects of age and communication level on eye contact in fragile X males and non-fragile X autistic males. Am J Med Genet. 1991b;38(2–3):498–502.

    Article  PubMed  Google Scholar 

  • Cohen IL, Nolin SL, Sudhalter V, Ding XH, Dobkin CS, Brown WT. Mosaicism for the FMR1 gene influences adaptive skills development in fragile X-affected males. Am J Med Genet. 1996;64(2):365–9.

    Article  PubMed  Google Scholar 

  • Cohen IL, Liu X, Schutz C, et al. Association of autism severity with a monoamine oxidase A functional polymorphism. Clin Genet. 2003a;64:190–7.

    Article  PubMed  Google Scholar 

  • Cohen IL, Schmidt-Lackner S, Romanczyk R, Sudhalter V. The PDD behavior inventory: a rating scale for assessing response to intervention in children with PDD. J Autism Dev Disord. 2003b;33(1):31–45.

    Article  PubMed  Google Scholar 

  • Cohen IL, Gomez TR, Gonzalez MG, Lennon EM, Karmel BZ, Gardner JM. Parent PDD behavior inventory profiles of young children classified according to autism diagnostic observation schedule-generic and autism diagnostic interview-revised criteria. J Autism Dev Disord. 2010a;40(2):246–54.

    Article  PubMed  Google Scholar 

  • Cohen IL, Liu X, Lewis ME, et al. Autism severity is associated with child and maternal MAOA genotypes. Clin Genet. 2010b;79(4):355–62.

    Article  Google Scholar 

  • Coleman M, Gillberg C. The autisms. New York: Oxford University Press; 2012.

    Google Scholar 

  • Constantino JN, Davis SA, Todd RD, et al. Validation of a brief quantitative measure of autistic traits: comparison of the social responsiveness scale with the autism diagnostic interview-revised. J Autism Dev Disord. 2003;33(4):427–33.

    Article  PubMed  Google Scholar 

  • Cote F, Fligny C, Bayard E, et al. Maternal serotonin is crucial for murine embryonic development. Proc Natl Acad Sci USA. 2007;104(1):329–34.

    Article  PubMed  Google Scholar 

  • Croen LA, Najjar DV, Ray GT, Lotspeich L, Bernal P. A comparison of health care utilization and costs of children with and without autism spectrum disorders in a large group-model health plan. Pediatrics. 2006;118(4):e1203–11.

    Article  PubMed  Google Scholar 

  • Davis LK, Hazlett HC, Librant AL, et al. Cortical enlargement in autism is associated with a functional VNTR in the monoamine oxidase A gene. Am J Med Genet B Neuropsychiatr Genet. 2008;147B:1145–51. 5 Oct 2008.

    Article  PubMed  Google Scholar 

  • Dawson G, Rogers S, Munson J, et al. Randomized, controlled trial of an intervention for toddlers with autism: the early start Denver model. Pediatrics. 2010;125(1):e17–23.

    Article  PubMed  Google Scholar 

  • Deckert J, Catalano M, Syagailo YV, et al. Excess of high activity monoamine oxidase A gene promoter alleles in female patients with panic disorder. Hum Mol Genet. 1999;8(4):621–4.

    Article  PubMed  Google Scholar 

  • Denney RM, Koch H, Craig IW. Association between monoamine oxidase A activity in human male skin fibroblasts and genotype of the MAOA promoter-associated variable number tandem repeat. Hum Genet. 1999;105:542–51.

    Article  PubMed  Google Scholar 

  • Du L, Bakish D, Ravindran A, Hrdina PD. MAO-A gene polymorphisms are associated with major depression and sleep disturbance in males. Neuroreport. 2004;15(13):2097–101.

    Article  PubMed  Google Scholar 

  • Filipek PA, Accardo PJ, Ashwal S, et al. Practice parameter: screening and diagnosis of autism: report of the quality standards subcommittee of the American academy of neurology and the child neurology society. Neurology. 2000;55(4):468–79.

    Article  PubMed  Google Scholar 

  • Gotham K, Pickles A, Lord C. Standardizing ADOS scores for a measure of severity in autism spectrum disorders. J Autism Dev Disord. 2009;39(5):693–705.

    Article  PubMed  Google Scholar 

  • Green DM, Swets JA. Signal detection theory and psychophysics. New York: Wiley; 1966.

    Google Scholar 

  • Happe F, Ronald A. The ‘fractionable autism triad’: a review of evidence from behavioural, genetic, cognitive and neural research. Neuropsychol Rev. 2008;18:287–304.

    Article  PubMed  Google Scholar 

  • Herman AI, Kaiss KM, Ma R, et al. Serotonin transporter promoter polymorphism and monoamine oxidase type A VNTR allelic variants together influence alcohol binge drinking risk in young women. Am J Med Genet B Neuropsychiatr Genet. 2005;133B(1):74–8.

    Article  PubMed  Google Scholar 

  • Johnson CP, Myers SM. Identification and evaluation of children with autism spectrum disorders. Pediatrics. 2007;120(5):1183–215.

    Article  PubMed  Google Scholar 

  • Karmel BZ, Gardner JM, Meade LS, et al. Early medical and behavioral characteristics of NICU infants later classified with ASD. Pediatrics. 2010;126(3):457–67.

    Article  PubMed  Google Scholar 

  • Kim J, Wigram T, Gold C. The effects of improvisational music therapy on joint attention behaviors in autistic children: a randomized controlled study. J Autism Dev Disord. 2008;38(9):1758–66.

    Article  PubMed  Google Scholar 

  • Komoto J, Usui S, Otsuki S, Terao A. Infantile autism and Duchenne muscular dystrophy. J Autism Dev Disord. 1984;14(2):191–5.

    Article  PubMed  Google Scholar 

  • Liu X, Malenfant P, Reesor C, et al. 2p15-p16.1 microdeletion syndrome: molecular characterization and association of the OTX1 and XPO1 genes with autism spectrum disorders. Eur J Hum Genet. 2011;19(12):1264–70.

    Article  PubMed  Google Scholar 

  • Lord C, Rutter M, Le Couteur A. Autism diagnostic interview-revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J Autism Dev Disord. 1994;24:659–85.

    Article  PubMed  Google Scholar 

  • Lord C, Rutter M, DiLavore PC, Risi S. Autism diagnostic observation schedule (ADOS). Los Angeles: Western Psychological Services; 1999. Manual ed.

    Google Scholar 

  • Malenfant P, Liu X, Hudson ML, et al. Association of GTF2i in the Williams-Beuren syndrome critical region with autism spectrum disorders. J Autism Dev Disord. 2012;42(7):1459–69.

    Article  PubMed  Google Scholar 

  • Malmberg K, Wargelius HL, Lichtenstein P, Oreland L, Larsson JO. ADHD and disruptive behavior scores – associations with MAO-a and 5-HTT genes and with platelet MAO-B activity in adolescents. BMC Psychiatry. 2008;8:28. 23 Apr 2008.

    Article  PubMed  Google Scholar 

  • Maron E, Lang A, Tasa G, et al. Associations between serotonin-related gene polymorphisms and panic disorder. Int J Neuropsychopharmacol. 2005;8(2):261–6.

    Article  PubMed  Google Scholar 

  • May ME, Srour A, Hedges LK, et al. Monoamine oxidase a promoter gene associated with problem behavior in adults with intellectual/developmental disabilities. Am J Intellect Dev Disabil. 2009;114(4):269–73.

    Article  PubMed  Google Scholar 

  • New York State Department of Health. Clinical practice guideline: report of the recommendations, autism/pervasive developmental disorders. In: Assessment and intervention for young children, (age 0–3 years). Albany: New York State Department of Health; 1999.

    Google Scholar 

  • Passamonti L, Fera F, Magariello A, et al. Monoamine oxidase-a genetic variations influence brain activity associated with inhibitory control: new insight into the neural correlates of impulsivity. Biol Psychiatry. 2006;59(4):334–40.

    Article  PubMed  Google Scholar 

  • Robins DL, Fein D, Barton ML, Green JA. The modified checklist for autism in toddlers: an initial study investigating the early detection of autism and pervasive developmental disorders. J Autism Dev Disord. 2001;31(2):131–44.

    Article  PubMed  Google Scholar 

  • Roohi J, DeVincent CJ, Hatchwell E, Gadow KD. Association of a monoamine oxidase-a gene promoter polymorphism with ADHD and anxiety in boys with autism spectrum disorder. J Autism Dev Disord. 2009;39(1):67–74.

    Article  PubMed  Google Scholar 

  • Sabol SZ, Hu S, Hamer D. A functional polymorphism in the monoamine oxidase A gene promoter. Hum Genet. 1998;103(3):273–9.

    Article  PubMed  Google Scholar 

  • Silva LM, Schalock M, Ayres R, Bunse C, Budden S. Qigong massage treatment for sensory and self-regulation problems in young children with autism: a randomized controlled trial. Am J Occup Ther. 2009;63(4):423–32.

    Article  PubMed  Google Scholar 

  • Sjoberg RL, Ducci F, Barr CS, et al. A non-additive interaction of a functional MAO-A VNTR and testosterone predicts antisocial behavior. Neuropsychopharmacology. 2008;33(2):425–30.

    Article  PubMed  Google Scholar 

  • Sparrow SS, Cicchetti DV, Balla DA. Vineland-II survey forms manual. Minneapolis: Pearson; 2005.

    Google Scholar 

  • Stone WL, McMahon CR, Henderson LM. Use of the screening tool for autism in two-year-olds (STAT) for children under 24 months: an exploratory study. Autism. 2008;12(5):557–73.

    Article  PubMed  Google Scholar 

  • Warren Z, McPheeters ML, Sathe N, Foss-Feig JH, Glasser A, Veenstra-VanderWeele J. A systematic review of early intensive intervention for autism spectrum disorders. Pediatrics. 2011;127(5):e1303–11.

    Article  PubMed  Google Scholar 

  • Wu JY, Kuban KC, Allred E, Shapiro F, Darras BT. Association of Duchenne muscular dystrophy with autism spectrum disorder. J Child Neurol. 2005;20(10):790–5.

    Article  PubMed  Google Scholar 

  • Zwaigenbaum L, Tarnopolsky M. Two children with muscular dystrophies ascertained due to referral for diagnosis of autism. J Autism Dev Disord. 2003;33(2):193–9.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Psychology, NYS Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Rd., 10314, Staten Island, NY, USA

    Ira L. Cohen

Authors
  1. Ira L. Cohen
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Ira L. Cohen .

Editor information

Editors and Affiliations

  1. Department of Biomedical Sciences, University of Westminster, Faculty of Science & Technology, London, United Kingdom

    Vinood B. Patel

  2. Nutritional Sciences Division and Genomics Centre, King's College London, London, United Kingdom

    Victor R. Preedy

  3. Faculty of Society and Health, Buckinghamshire New University, Middlesex, United Kingdom

    Colin R. Martin

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer Science+Business Media New York

About this entry

Cite this entry

Cohen, I.L. (2014). PDD Behavior Inventories: Clinical and Research Applications to ASD. In: Patel, V., Preedy, V., Martin, C. (eds) Comprehensive Guide to Autism. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-4788-7_171

Download citation

  • DOI: https://doi.org/10.1007/978-1-4614-4788-7_171

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-4787-0

  • Online ISBN: 978-1-4614-4788-7

  • eBook Packages: Behavioral Science

Publish with us

Policies and ethics

Search

Navigation