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Spinal Infections: Evidence-Based Neuroimaging

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Evidence-Based Neuroimaging Diagnosis and Treatment

Part of the book series: Evidence-Based Imaging ((Evidence-Based Imag.))

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Abstract

The three most common sources of vertebral osteomyelitis and discitis are (1) hematogenous spread, (2) direct inoculation due to interventions such as spinal fixation, or (3) spread from an adjacent site of infection such as a paraspinal abscesses [1–4]. Among patients with no risk factors for vertebral osteomyelitis and discitis, Staphylococcus aureus is the most common pathogen and is isolated from as much as 50 % of patients. Other organisms are more common among patients with risk factors such as spinal surgeries with internal fixation devices (Escherichia coli, coagulase-negative staphylococci, and Propionibacterium acnes) [1, 3–5], genitourinary tract instrumentations (E. coli) [1, 4, 6], IV drug abuse (Pseudomonas and Candida) [2, 5–10], and central line placements (Candida) [7, 11]. Mycobacterium tuberculosis and Salmonella should also be taken into consideration particularly if the patient is an immigrant from a developing country or has a recent history of travel to an area where these infections are endemic [12]. In general, lumbar spine is the most common site for vertebral osteomyelitis and discitis, followed by the thoracic and cervical spine [5, 13, 14].

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Roudsari, B., Jarvik, J.G. (2013). Spinal Infections: Evidence-Based Neuroimaging. In: Medina, L.S., Sanelli, P.C., Jarvik, J.G. (eds) Evidence-Based Neuroimaging Diagnosis and Treatment. Evidence-Based Imaging. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3320-0_33

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