Premalignant and Malignant Tumors of the Vulva

  • Edward J. WilkinsonEmail author
  • Demaretta S. Rush
Living reference work entry


Terminology for vulvar squamous intraepithelial lesions (SILs) has undergone considerable evolution as the biology of these lesions becomes better understood. The current terminology of “squamous intraepithelial lesions” replaces the previously used terms of dysplasia, carcinoma in situ, vulvar intraepithelial neoplasia (VIN), Bowen disease, Bowenoid dysplasia, and others. These changes were accepted by the World Health Organization (WHO) in concurrence with the College of American Pathologists and a number of leading medical organizations (American College of Obstetricians and Gynecologists (ACOG), American Society for Colposcopy and Cervical Pathology (ASCCP), International Society for the study of Vulvar Vaginal Disease (ISSVD), and others) and are summarized in Table 1 (Bornstein et al. 2016; Crum et al. 2014; Darragh et al. 2012; Wilkinson et al. 2015).


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Authors and Affiliations

  1. 1.Department of Pathology, Immunology and Laboratory MedicineUniversity of Florida College of MedicineGainesvilleUSA
  2. 2.Department of PathologyUniversity of Arizona College of MedicineTusconUSA

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