Hormone Effects on Behavior

Reference work entry


During the last century, clues that hormones might affect behavior arose both from laboratory experiments and in the clinic. Frank Beach, working with animals at the University of California, Berkeley, demonstrated the activation of male sexual behavior by testosterone injections, as well as the facilitation of female sexual behavior by treatments with estrogens and progesterone. In the clinic, it was clear that hyperthyroid patients could be nervous and irritable, while hypothyroid patients would be sluggish and dull. As well, eunuchs (lacking testosterone from the testes) had no libido, and thus, clinical experience went hand in hand with Beach’s experimental demonstration.


Precocious Puberty Oxytocin Receptor Stria Terminalis Medial Preoptic Area Medial Amygdala 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



A-melanocyte-stimulating hormone


Adrenocorticotropin hormone


Attention deficit hyperactivity disorder


Agouti-related peptide


Cyclic adenosine monophosphate


Cornu ammonis region (hippocampus)




Corticotropin-releasing hormone




Deoxyribonucleic acid




Elevated-plus maze


Estrogen receptor


Generalized anxiety disorder








Messenger ribonucleic acid


Neuropeptide Y


Postnatal day


Posttraumatic stress disorder


Paraventricular nucleus of the hypothalamus


Small nucleotide polymorphism

Further Reading

  1. Blanchard DC, McKittrick CR, Hardy MP, Blanchard RJ (2002) Effects of social stress on hormones, brain, and behavior. In: Pfaff DW, Arnold AP, Etgen AM, Fahrbach SE, Rubin RT (eds) Hormones, brain and behavior, vol 1. Academic, Amsterdam, pp 735–772CrossRefGoogle Scholar
  2. Choleris E, Gustafsson JA, Korach KS, Muglia LJ, Pfaff DW, Ogawa S (2003) An estrogen-dependent four-gene micronet regulating social recognition: a study with oxytocin and estrogen receptor-alpha and -beta knockout mice. Proc Natl Acad Sci USA 100(10):6192–6197PubMedCrossRefGoogle Scholar
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Copyright information

© Springer Science+Business Media, LLC 2013

Authors and Affiliations

  1. 1.Laboratory of Neurobiology and BehaviorThe Rockefeller UniversityNew YorkUSA

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