Definitions
Coagulation: blood clotting
Gla: γ-carboxyglutamic acid is formed by posttranslational addition of a carboxyl group to the γ-carbon of glutamic acid
Thrombosis: formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system
Procofactors: proteins whose binding to another coagulation protein requires proteolytic cleavage for full activity of the complex
Tenase complex: a complex formed by the assembly of factors IXa and VIIIa on a cell membrane that converts factor X to active factor Xa
Prothrombinase complex: a complex formed by the association of factors Va and Xa on a cell membrane that converts prothrombin to thrombin
EGF-like domain: a protein domain conserved through evolution that includes an N-terminal two-stranded beta-sheet followed by a loop and a short C-terminal two-stranded beta-sheet
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Bowley, S.R., Huang, M., Furie, B.C., Furie, B. (2013). Blood Clotting Proteins. In: Kretsinger, R.H., Uversky, V.N., Permyakov, E.A. (eds) Encyclopedia of Metalloproteins. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-1533-6_46
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DOI: https://doi.org/10.1007/978-1-4614-1533-6_46
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