Bacterial Tellurite Resistance
Bacteria resistance to tellurite is defined here as specific genes, cluster of genes, or specific genetic operons referred to as resistance determinants. Tellurite (TeO32−), redox state Te(IV), is the oxyanion of the chalcogen tellurium (Te; atomic number 52) in group 16 with elements O, S, Se, and Po. In addition to specific determinants a number of bacteria species have been identified to have high levels of resistance to tellurite yet the specific genetics has not been defined; these are referred to as tellurite tolerant.
Bacteria treat tellurite quite differently from other antibacterial metal ions. Evolution has seen that a biochemical mechanism of resistance is uniform across species for most all other metal ions other than tellurite. At least five genetically different resistance determinants have been identified with little to no homology between them. Genes...
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