This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Allard JB, Brock TG (2005) Structural organization of the regulatory domain of human 5-lipoxygenase. Curr Protein Pept Sci 6(2):125–131
Chahinian H, Sias B et al (2000) The C-terminal domain of pancreatic lipase: functional and structural analogies with c2 domains. Curr Protein Pept Sci 1(1):91–103
Cho W, Stahelin RV (2006) Membrane binding and subcellular targeting of C2 domains. Biochim Biophys Acta 1761(8):838–849
Huang CH, Mandelker D et al (2007) The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations. Science 318(5857):1744–1748
Lemmon MA (2008) Membrane recognition by phospholipid-binding domains. Nat Rev Mol Cell Biol 9(2):99–111
Leslie NR, Downes CP (2002) PTEN: the down side of PI 3-kinase signalling. Cell Signal 14(4):285–295
Nalefski EA, Falke JJ (1996) The C2 domain calcium-binding motif: structural and functional diversity. Protein Sci 5(12):2375–2390
Pipkin ME, Lieberman J (2007) Delivering the kiss of death: progress on understanding how perforin works. Curr Opin Immunol 19(3):301–308
Popoff MR, Bouvet P (2009) Clostridial toxins. Future Microbiol 4(8):1021–1064
Rhee SG (2001) Regulation of phosphoinositide-specific phospholipase C. Annu Rev Biochem 70:281–312
Rizo J, Sudhof TC (1998) C2-domains, structure and function of a universal Ca2+ −binding domain. J Biol Chem 273(26):15879–15882
Sudhof TC (2004) The synaptic vesicle cycle. Annu Rev Neurosci 27:509–547
Zhang D, Aravind L (2010) Identification of novel families and classification of the C2 domain superfamily elucidate the origin and evolution of membrane targeting activities in eukaryotes. Gene 469(1–2):18–30
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer Science+Business Media New York
About this entry
Cite this entry
Leonard, T.A. (2013). C2 Domain Proteins. In: Kretsinger, R.H., Uversky, V.N., Permyakov, E.A. (eds) Encyclopedia of Metalloproteins. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-1533-6_39
Download citation
DOI: https://doi.org/10.1007/978-1-4614-1533-6_39
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4614-1532-9
Online ISBN: 978-1-4614-1533-6
eBook Packages: Biomedical and Life SciencesReference Module Biomedical and Life Sciences