Encyclopedia of Metalloproteins

2013 Edition
| Editors: Robert H. Kretsinger, Vladimir N. Uversky, Eugene A. Permyakov

Ribonucleotide Reductase

Reference work entry
DOI: https://doi.org/10.1007/978-1-4614-1533-6_360

Synonyms

 RNR; also see Table 1
Ribonucleotide Reductase, Table 1

Gene, subunit, and protein names of RNR enzymes

RNR class

Gene name

Polypeptide name

Quaternary structures of active holoenzyme

General and synonymous protein names

I

NrdA

α

α2β2 (general), α6β2-6(mammals, yeast)

NrdA, R1

M1, RR1 (mammals), RNR1 (yeast), RNR3 (yeast)

NrdB

β

NrdB, R2

M2, RR2 (mammals), p53R2, RR2B (p53-regulated R2, mammals), RNR2 (yeast), RNR4 (yeast)

Ib

NrdE

α

α2β2

NrdE, R1E

NrdF

β

NrdF, R2F

NrdI

n.a.a

NrdI(flavodoxin)

Ic

NrdA

α

α2β2

NrdA, R1

NrdBPhe/Leu/Val

βPhe/Leu/Val

NrdBPhe/Leu/Val, R2Phe/Leu/Val

II

NrdJ

α

α or α2

NrdJ

III

NrdD

α

α2

NrdD

NrdG

n.a.a

NrdG(activase)

an.a., not applicable

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References

  1. Andersson KK (ed) (2008) Ribonucleotide reductase. Nova Science, HauppageGoogle Scholar
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  11. Sjöberg B-M (2010) Biochemistry. A never-ending story. Science 329:1475–1476PubMedCrossRefGoogle Scholar
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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of Biochemistry and BiophysicsStockholm UniversityStockholmSweden