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Biomarkers for Cadmium

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References

  • ATSDR (2008) Toxicological profile for cadmium. http://www.atsdr.cdc.gov/cercla/toxprofiles/tp5.html

  • Bernard A (2004) Renal dysfunction induced by cadmium: biomarkers of critical effects. Biometals 17:519–523

    Article  PubMed  CAS  Google Scholar 

  • Chen L, Jin T, Huang B et al (2006) Critical exposure level of cadmium for elevated urinary metallothionein–an occupational population study in China. Toxicol Appl Pharmacol 215:93–99

    Article  PubMed  CAS  Google Scholar 

  • Garcon G, Leleu B, Marez T et al (2007) Biomonitoring of the adverse effects induced by the chronic exposure to lead and cadmium on kidney function: usefulness of alpha-glutathione S-transferase. Sci Total Environ 377:165–172

    Article  PubMed  CAS  Google Scholar 

  • Huang J (2004) Chinese National health standards for occupational exposure to cadmium and diagnostic criteria of occupational chronic cadmium poisoning. Biometals 17(5):511. doi:10.1023/B:BIOM.0000045833.30776.84

    Article  CAS  Google Scholar 

  • Jarup L, Akesson A (2009) Current status of cadmium as an environmental health problem. Toxicol Appl Pharmacol 238:201–208

    Article  PubMed  CAS  Google Scholar 

  • Jin T, Nordberg G, Wu X et al (1999) Urinary N-acetyl-beta-D-glucosaminidase isoenzymes as biomarker of renal dysfunction caused by cadmium in a general population. Environ Res 81:167–173

    Article  PubMed  CAS  Google Scholar 

  • Moriguchi J, Inoue Y, Kamiyama S et al (2009) N-acetyl-beta-D-glucosaminidase (NAG) as the most sensitive marker of tubular dysfunction for monitoring residents in non-polluted areas. Toxicol Lett 190:1–8

    Article  PubMed  CAS  Google Scholar 

  • Noonan CW, Sarasua SM, Campagna D et al (2002) Effects of exposure to low levels of environmental cadmium on renal biomarkers. Environ Health Perspect 110:151–155

    Article  PubMed  CAS  Google Scholar 

  • Prozialeck WC, Edwards JR (2010) Early biomarkers of cadmium exposure and nephrotoxicity. Biometals 23:793–809

    Article  PubMed  CAS  Google Scholar 

  • Prozialeck WC, Vaidya VS, Liu J et al (2007) Kidney injury molecule-1 is an early biomarker of cadmium nephrotoxicity. Kidney Int 72:985–993

    Article  PubMed  CAS  Google Scholar 

  • Prozialeck WC, Edwards JR, Lamar PC et al (2009a) Expression of kidney injury molecule-1 (Kim-1) in relation to necrosis and apoptosis during the early stages of Cd-induced proximal tubule injury. Toxicol Appl Pharmacol 238:306–314

    Article  PubMed  CAS  Google Scholar 

  • Prozialeck WC, Edwards JR, Vaidya VS et al (2009b) Preclinical evaluation of novel urinary biomarkers of cadmium nephrotoxicity. Toxicol Appl Pharmacol 238:301–305

    Article  PubMed  CAS  Google Scholar 

  • Shaikh ZA, Smith LM (1986) Biological indicators of cadmium exposure and toxicity. Experientia Suppl 50:124–130

    Article  PubMed  CAS  Google Scholar 

  • Suwazono Y, Sand S, Vahter M et al (2006) Benchmark dose for cadmium-induced renal effects in humans. Environ Health Perspect 114:1072–1076

    Article  PubMed  CAS  Google Scholar 

  • Uno T, Kobayashi E, Suwazono Y et al (2005) Health effects of cadmium exposure in the general environment in Japan with special reference to the lower limit of the benchmark dose as the threshold level of urinary cadmium. Scand J Work Environ Health 31:307–315

    Article  PubMed  CAS  Google Scholar 

  • Vaidya VS, Ferguson MA, Bonventre JV (2008) Biomarkers of acute kidney injury. Annu Rev Pharmacol Toxicol 48:463–493

    Article  PubMed  CAS  Google Scholar 

  • Weaver VM, Kim NS, Jaar BG et al (2011) Associations of low-level urine cadmium with kidney function in lead workers. Occup Environ Med 68(4):250–256

    Article  PubMed  CAS  Google Scholar 

  • World Health Organization (WHO) (2000) Cadmium. http://www.euro.who.int/document/aiq/6_3cadmium.pdf

  • Wu X, Jin T, Wang Z et al (2001) Urinary calcium as a biomarker of renal dysfunction in a general population exposed to cadmium. J Occup Environ Med 43:898–904

    Article  PubMed  CAS  Google Scholar 

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Correspondence to Walter C. Prozialeck .

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Prozialeck, W.C. (2013). Biomarkers for Cadmium. In: Kretsinger, R.H., Uversky, V.N., Permyakov, E.A. (eds) Encyclopedia of Metalloproteins. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-1533-6_33

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