Encyclopedia of Metalloproteins

2013 Edition
| Editors: Robert H. Kretsinger, Vladimir N. Uversky, Eugene A. Permyakov

Bacterial Calcium Binding Proteins

Reference work entry
DOI: https://doi.org/10.1007/978-1-4614-1533-6_266

Synonyms

Definition

Bacterial proteins that bind calcium and are implicated in the regulation of various cellular events. These proteins appear to be involved in a wide variety of functions including chemotaxis, heat shock, pathogenesis, transport (influx and efflux), cell differentiation, and cell signaling.

Background

The calcium ion (Ca2+) is perhaps the most important intracellular messenger in eukaryotes and regulates many cellular processes including cell differentiation, movement, cell cycle, transport mechanisms, and gene expression (Celio et al. 1996). Many effects of Ca2+ are mediated by  calcium-binding proteins (CaBPs). Some of these proteins act as Ca2+ reservoirs or buffers. More specialized CaBPs such as calmodulin, act as signal transducers activating phosphorylation cascades leading to regulation in gene expression, and control of Ca2+ channel activity.

In prokaryotes, a similar role for Ca2+has been proposed...

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References

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.College of Health SciencesThe University of Texas at El PasoEl PasoUSA
  2. 2.Department of Microbiology and Molecular Genetics, College of Arts and SciencesOklahoma State UniversityStillwaterUSA