Encyclopedia of Metalloproteins

2013 Edition
| Editors: Robert H. Kretsinger, Vladimir N. Uversky, Eugene A. Permyakov

Barium and Protein–RNA Interactions

Reference work entry
DOI: https://doi.org/10.1007/978-1-4614-1533-6_169



Genomic studies are providing researchers with a potentially complete list of the molecular components present in living systems. It is now obvious that several metal ions are essential to life. More specifically, biological macromolecules (proteins and nucleic acids) that require metal ions to perform their physiological functions are widespread in all organisms. Here, we explored the importance and involvement of one of the alkali earth metals, barium, in the biological system. Based on structural and functional analyses, we clearly demonstrated how the divalent metal ions produce the structural rearrangements that are required for hut mRNA recognition. The applications and health risks of barium metal ions are also discussed.

General Background on Barium Metal

The chemical element barium is the 56th element in the chemical periodic table with the symbol of

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.RIKEN SPring-8 CenterHarima InstituteHyogoJapan