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Barium Binding to EF-Hand Proteins and Potassium Channels

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Encyclopedia of Metalloproteins

Synonyms

Ca2+-activated K+ channels; Calcium-modulated potassium channels; Calmodulin; EF-hand calcium-binding proteins; Potassium channels

Definition

Barium can effectively interact with several EF-hand calcium-binding proteins. This metal ion is also considered as a potent inhibitor of the regulated potassium channels. It also can inactivate some calcium channels.

Some Physicochemical Properties of Barium

The chemical element barium is the 56th element in the chemical periodic table with the symbol of Ba, atomic number of 56, and atomic mass of the 137.33. It belongs to the group 2 (of which it is a fifth element) in the periodic table. Therefore, barium, which is a soft, silvery-white metal, with a slight golden shade when ultrapure, and highly reactive metal, is the heaviest nonradioactive member of the alkaline-earth elements. Barium is a relatively common element in Earth (it has a concentration of 0.0425% in the Earth’s crust and 13 Î¼g/L in sea water, being 14th in natural...

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Correspondence to Vladimir N. Uversky Ph.D., D.Sc. .

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Uversky, V.N. (2013). Barium Binding to EF-Hand Proteins and Potassium Channels. In: Kretsinger, R.H., Uversky, V.N., Permyakov, E.A. (eds) Encyclopedia of Metalloproteins. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-1533-6_168

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