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Diabetic Embryopathy

Reference work entry

Maternal diabetes adversely affects the fetus during pregnancy. The risk of developing congenital malformations has been well documented (Reece and Homko 2000; Correa et al. 2008). The frequency of congenital anomalies among insulin-dependent diabetic offspring is estimated at 3–6% of all infants at birth, representing a twofold to threefold increase, when compared with nondiabetics (Reece and Hobbins 1986).

Synonyms and Related Disorders

Infant of diabetic mother

Genetics/Basic Defects

  1. 1.
    Teratogenicity of maternal diabetes mellitus in human
    1. a.

      Occurring during embryogenesis at the end of blastogenesis and organogenesis between third and seventh weeks of gestation

       
    2. b.

      Leading to a spectrum of malformations known as diabetic embryopathy

       
     
  2. 2.
    Diabetic fetopathy
    1. a.

      Occurs during fetal development (after the tenth week of gestation)

       
    2. b.

      Not associated with malformations

       
    3. c.

      Fetal hyperinsulinism: the cause of macrosomia and numerous other postnatal complications

       
     
  3. 3.
    Potential...

Keywords

Gestational Diabetes Mellitus Congenital Malformation Diabetic Mother Situs Inversus Maternal Diabetes 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

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© Springer Science+Business Media, LLC 2012

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