Congenital Toxoplasmosis

Reference work entry

Acute infection in a pregnant woman with a parasite, Toxoplasma gondii, can have serious consequences on the fetus, ranging from fetal loss to severe neurologic or ocular lesions. In other cases, infected newborns are asymptomatic at birth, but are at risk for developing retinal diseases during childhood or adolescence on Toxoplasma reactivation (Wallon et al. 2004). In the United States, the incidence of congenital toxoplasmosis is estimated to be 1 in 1,000 to 1 in 10,000 births and approximately 400–4,000 cases of congenital toxoplasmosis occur each year.

Synonyms and Related Disorders

Toxoplasma gondii infection in pregnancy

Genetics/Basic Defects

  1. 1.
    Toxoplasma gondii (Beasley and Egerman 1998)
    1. a.

      A protozoan parasite

    2. b.

      The causative agent of toxoplasmosis, a common infection throughout the world with estimated one billion people infected worldwide

    3. c.
      Life cycle: exists in three forms
      1. i.

        The oocysts, or soil form

      2. ii.

        The tachyzoite, or active infectious form

      3. iii.



Congenital Infection Maternal Infection Congenital Toxoplasmosis Toxoplasma Infection Fetal Infection 
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