Collodion baby is a descriptive term for infants born encased in a membrane-like thick scale resembling oiled parchment or collodion. The presence of a collodion membrane at birth represents a defect in skin barrier function and is usually the initial presentation of a congenital ichthyosiform disorder, most often autosomal recessive congenital ichthyosis (ARCI). Thus, neonates born with the features of collodion baby subsequently develop lamellar ichthyosis (LI), nonbullous congenital ichthyosiform erythroderma (NCIE), or other forms of ichthyosis (Akiyama 2006). However, in 10% of neonates spontaneous healing occurs (Raghunath et al. 2003). Collodion baby is a rare congenital condition accounting for 1 in 50,000–1 in 100,000 deliveries.
Synonyms and Related Disorders
Collodion fetus; Ichthyosis congenita; Lamellar exfoliation of newborn; Lamellar ichthyosis
KeywordsStratum Corneum Gauche Disease Congenital Hypothyroidism Skin Barrier Function Gauche Disease Type
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