Cerebral palsy (CP) is currently considered as a clinically defined symptom complex applied to individuals with a static, nonprogressive motor impairment of early onset that is cerebral in origin. It describes a group of motor impairment syndromes secondary to genetic and acquired disorders of the developing brain. Therefore, it is not a single entity with respect to pathogenesis but rather an etiologically heterogeneous entity with multiple possible causes that result in an aberration or injury to the maturing central nervous system. The motor disorders of cerebral palsy are often accompanied by disturbances of sensation, cognition, communication, perception, and/or behavior, and/or by a seizure disorder. The prevalence is estimated between 1.5 and 2.5 per 1,000 live births.
Synonyms and Related Disorders
Ataxic-hypotonic CP; Dyskinetic CP; Mixed CP;Monoplegic/hemiplegic CP; Spastic diplegic CP; Spastic quadriplegic CP; Spastic triplegic CP
Genetics/Basic Defects
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(2012). Cerebral Palsy. In: Chen, H. (eds) Atlas of Genetic Diagnosis and Counseling. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-1037-9_35
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DOI: https://doi.org/10.1007/978-1-4614-1037-9_35
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