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Elegantine

Reference work entry

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Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Miscellaneous Alkaloids

Biological sources: Saussurea elegans

C23H29NO5: 399.2046

Mp: 190–192°C (MeOH), 210°C (dec., hydrobromide) [1]; 162°C (product of saponification) [1, 2]

[α]D +75° (DMFA) [1]

Solubility: spar. sol. org. solvs. [1]

UV: 224, 276(3.24, 2.56) [1]

IR: 3250, 1765, 1640, 1595, 1520, 910 [1]

1H NMR (Py-d5, product of saponification): 3.89(1H, m), 4.12(1H, t, J = 8.5), 4.61(1H, t, J = 7; 2; 1.9), 4.91, 5.01(each 1H, d, J = 2), 5.47(4H, br s), 6.21, 6.30(each 1H, d) [3]

Pharm./Biol.: Hypertensive effect [4]

References

  1. 1.
    A.M. Khashimov, L.S. Smirnova, S.F. Matkhalikova, S.Yu. Yunusov, Chem. Nat. Comp. 4, 310 (1968)CrossRefGoogle Scholar
  2. 2.
    L.S. Smirnova, A.M. Khashimov, S.Yu. Yunusov, Chem. Nat. Comp. 5, 56 (1969)CrossRefGoogle Scholar
  3. 3.
    I.D. Sham’yanov, N.D. Abdullaev, G.P. Sidyakin, K. Taizhanov, Khim. Prirod. Soedin. 667 (1981)Google Scholar
  4. 4.
    Kh.U. Aliev, Farmakologiya alkaloidov i serdechnykh glikozidov (FAN, Tashkent, 1971), p. 195Google Scholar

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© Springer Science+Business Media New York 2013

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