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Thermopsine

Reference work entry

CAS Registry Number: 486-90-8 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Quinolizidine Alkaloids

Biological sources: Cytisus laburnum, Thermopsis alpina, T. alterniflora, T. dolichocarpa, T. fabacea, T. lanceolata, T. turkestanica

C15H20N2O: 244.1576

Mp: 205–206°C (Me2CO), 209°C (picrate), 289°C (perchlorate), 242°C (dec., methiodide), 308°C (dec., hydroiodide) [1]

[α]D −161° (EtOH) [1]

Solubility: very sol. Et2O, EtOH, CHCl3, H2O; spar. sol. Me2CO, pet. ether [1]

UV: 235, 309(3.80, 3.90) [2]

IR: 3000, 2950, 2865, 2800, 2770, 2690, 1660, 1555, 1470, 1450, 1423, 1400, 1380, 1355, 1317, 1304, 1279, 1188, 1152, 1147, 1131, 1113, 1081, 1073, 1060, 1043, 1028, 976, 960, 861, 852, 838, 804 [2]

MSm/z: 244(M+, 26), 243(5), 229(4), 160(8), 146(13), 136(11), 122(10), 98(100), 97(12), 41(19) [3]

1H NMR: 1.70(Ha-15), 1.84(2H, H-8), 2.00(H-9), 2.29(Ha-17), 2.53(He-15), 2.74(He-17), 2.85(H-7), 3.56(Ha-10), 4.20(He-10) [4]

13 C NMR: [ 5]

Table 1

C-2

References

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    S.W. Pelletier (ed.), Alkaloids, Chemical and Biological Perspectives, vol. 2 (Wiley, New York, 1984), p. 105Google Scholar
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    A.S. Sadykov, Kh.A. Aslanov, Yu.K. Kushmuradov, Alkaloids of the Quinolizidine Series [in Russian] (Nauka, Moscow, 1975), p. 217Google Scholar
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