Sophoramine

doi:10.1007/978-1-4614-0560-3_1258

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CAS Registry Number: 6882-66-2

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Quinolizidine Alkaloids

Biological sources: Leptorhabdos parviflora, Sophora alopecuroides, S. griffithii, S. pachycarpa

C₁₅H₂₀N₂O: 244.1576

Mp: 164–165°C (pet. ether), 231°C (picrate), 248°C (dec., hydrochloride), 175°C (picrolonate), 247°C (chloroplatinate), 296°C (hydroiodide) [1]

[α]_D −91° (EtOH)

Solubility: very sol. EtOH, C₆H₆, CHCl₃; sol. Et₂O, pet. ether; spar. sol. H₂O [1]

UV: 234, 310(3.80, 3.90) [2]

IR: 2800–2700, 1645, 1580, 1560 [2]

MS m/z: 244(M⁺, 94), 243(100), 229(3), 215(14), 201(13), 186(12), 159(8), 149(8), 136(21), 122(5), 110(8), 98(3), 97(4), 96(8), 82(7), 55(11) [3, 4]

HPLC. GC: [5]

Pharm./Biol.: Tranquilizing action. Prolongs sleep induced by hexenal and barbital sodium [6]

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Editors and Affiliations

S.Yu. Yunusov Institute of the Chemistry of Plant Substances of the Academy of Sciences of the Republic of Uzbekistan, Tashkent, Republic of Uzbekistan
Shakhnoza S. Azimova
S.Yu. Yunusov Institute of the Chemistry of Plant Substances of the Academy of Sciences of the Republic of Uzbekistan, Tashkent, Republic of Uzbekistan
Marat S. Yunusov

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(2013). Sophoramine. In: Azimova, S.S., Yunusov, M.S. (eds) Natural Compounds. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0560-3_1258

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DOI: https://doi.org/10.1007/978-1-4614-0560-3_1258
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4614-0559-7
Online ISBN: 978-1-4614-0560-3
eBook Packages: Chemistry and Materials ScienceReference Module Physical and Materials ScienceReference Module Chemistry, Materials and Physics

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