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Sophocarpine N-Oxide

Reference work entry

CAS Registry Number: 26904-64-3 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Quinolizidine Alkaloids

Biological sources: Ammothamnus lehmannii, Sophora alopecuroides, S. pachycarpa

C15H22N2O2: 262.1681

Mp: 208–210°C

[α]D +37° (EtOH) [1]

UV: 260(3.40) [1, 2]

IR: 950 [1]

MSm/z: 262(M+), 244, 245(100), 217, 215, 202, 191, 177, 160, 150, 138, 136, 134, 122, 110, 96, 80, 68, 55 [1, 2]

1H NMR: 2.02(J = 8, 10.8, 3.1, Ha-12), 2.57(J = 18, 6.1, 5.2, He-12). 3.97(J = 12, 5.4, He-17), 4.17 (J = 12, 12, Ha-17), 5.04(J = 10.8, 6.1, 10.8, H-11), 5.83(J = 9.5, 2.4, 1.2, H-14), 6.43(J = 9.5, 5.2, 3.1, H-13) [1]

GLC: [3]

HPLC, GC: [4]

Pharm./Biol.: In large doses possesses a stimulating action [5]

References

  1. 1.
    T.E. Monakhova, O.N. Tolkachev, V.S. Kabanov, N.F. Proskurnina, Chem. Nat. Comp. 10, 275 (1974)CrossRefGoogle Scholar
  2. 2.
    V.G. Zaikin, Z.S. Ziyavidinova, N.S. Vul’fson, Izv. AN SSSR, Ser. Khim. (8), 1734 (1974)Google Scholar
  3. 3.
    A. Ueno, K. Morinaga, S. Fukushima, S. Okuda, Chem. Pharm. Bull. 26, 1832 (1978)CrossRefGoogle Scholar
  4. 4.
    X. Chen, C.Q. Yi, X.Q. Yang, X. Wang, J. Chromatogr. B 812, 149 (2004)Google Scholar
  5. 5.
    T.E. Monakhova, Author’s Abstract of Candidate’s Dissertation, Moscow, 1975Google Scholar

Copyright information

© Springer Science+Business Media New York 2013

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