Sophocarpine

Reference work entry

CAS Registry Number: 6483-15-4 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Quinolizidine Alkaloids

Biological sources: Ammothamnus lehmannii, A. songoricus, Leontice smirnowii, Leptorhabdos parviflora, Sophora alopecuroides, S. flavescens, S. griffithii, S. japonica, S. pachycarpa, Vexibia pachycarpa

C15H22N2O: 246.1732

Mp: 53–55°C (Et2O) [1], 157°C (picrate), 202°C (methiodide), 82°C (hydrate) [2]

[α]D −29° (EtOH) [1]

UV: 260 [2]

IR: 2800–2700, 1670, 1645 [2]

MSm/z: 246(M+, 73), 245(100), 231(3), 203(20), 192(5), 188(6), 177(14), 160(12), 150(44), 137(23), 122(20), 110(13), 98(28), 97(9), 96(47), 83(28), 55(19) [3, 4]

1H NMR: 1.64(H-5), 1.80(2H, J = 11.2, Ha-2, Ha-10), 2.67(2H, J = 11.2, He-2, He-10), 2.92(1H, J = 12.8, 12.2, Ha-17), 3.85(H-11), 3.90(1H, J = 12.8, 4.7, He-17), 5.70(1H, dd, J = 10, 2, H-14), 6.40(1H, m, J = 10, 3, 3.5, H-13) [5]

1H NMR(300 MHz, CDCl3): 1.68(H-7), 1.79(H-5), 1.94(2H, m, H-2, H-10), 2.09(1H, t, J =...

References

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