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Piptanthine

Reference work entry

CAS Registry Number: 7344-67-4 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Quinolizidine Alkaloids

Biological sources: Piptanthus mongolicus, P. nanus

C20H35N3: 317.2831

Mp: 144–145°C (Me2CO) [1], 206°C (nitrate), 256°C (dec., hydrochloride), 286°C (dec., hydrobromide) [1];

[α]D −24° (EtOH) [1], −19° (c 0.1, CHCl3) [2]

IR: 3286 [3]

MSm/z: 317 (M+, 29), 234(52), 233(11), 219(14), 191(10), 151(22), 98(38), 96(13), 84(100), 56(14) [2]

Pharm./Biol.: LD50 173 mg/kg (s/c, mice). Lowers arterial pressure, strengthens respiration. Ganglioblocking action [4]

References

  1. 1.
    R.A. Konovalova, B.S. Diskina, M.S. Rabinovich, Zh. Obshch. Khim. 21, 773 (1951)Google Scholar
  2. 2.
    R. Torrenegra, P. Bauerei, H. Achenbach, Phytochemistry 28, 2219 (1989)CrossRefGoogle Scholar
  3. 3.
    U. Eisner, F. Sorm, Collect. Czech. Chem. Commun. 24, 2348 (1959)Google Scholar
  4. 4.
    F.S. Sadritdinov, A.G. Kurmukov, The Pharmacology of the Plant Alkaloids and Their Use in Medicine [in Russian] (UzSSR, Tashkent, 1980), p. 143Google Scholar

Copyright information

© Springer Science+Business Media New York 2013

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