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Pachycarpine [(+)-Sparteine]

Reference work entry

CAS Registry Number: 492-08-0 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Quinolizidine Alkaloids

Biological sources: Ammodendron argenteum, A. conollyi, A. eichwaldii, A. karelinii, A. longiracemosum, Ammothamnus lehmanii, Cytisus caucasicus, C. laburnum, Genista abchasica, Leontice ewersmannii, Leptorhabdos parviflora, Sophora griffithii, S. pachycarpa, Thermopsis alpina, T. alterniflora, T. dolichocarpa, T. fabacea, T. lanceolata, Vexibia pachycarpa

C15H26N2: 234.2096

Mp: 235°C (hydroiodide), 258°C (dihydroiodide), 173°C (perchlorate), 240°C (methiodide), 97°C (picrate), 208°C (dipicrate) [1]

[α]D +17° (EtOH)

IR: 2780, 2730 [2]

MSm/z: 234(M+), 193, 137, 136, 98(100), 97, 84, 55, 41 [3]

1H NMR: 0.90(1H, Ha-8), 1.30(1H, H-9). 1.65(1H, H-7), 1.87(2H, Ha-2, Ha-15), 1.90(1H, J = 10, 2, Ha-10), 2.02(1H, J = 11, He-8), 2.22(1H, J = 10, 2, Ha-17), 2.42(1H, J = 10, 2, He-10), 2.50(1H, J = 10, He-17), 2.56(2H, He-2, He-15) [4]

13 C NMR: [ 5]

T...

References

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    A.S. Sadykov, Kh.A. Aslanov, Yu.K. Kushmuradov, Alkaloids of the Quinolizidine Series [in Russian] (Nauka, Moscow, 1975), p. 217Google Scholar
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    F.S. Sadritdinov, A.G. Kurmukov, The Pharmacology of the Plant Alkaloids and Their Use in Medicine [in Russian] (UzSSR, Tashkent, 1980), p. 141Google Scholar
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    M.D. Mashkovskii, Drugs [in Russian], vol. 1 (Meditsina, Moscow, 1984), p. 255Google Scholar

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© Springer Science+Business Media New York 2013

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