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Neosophoramine

Reference work entry

CAS Registry Number: 52932-74-8 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Quinolizidine Alkaloids

Biological sources: Sophora alopecuroides

C15H20N2O: 244.1576

Mp: 124–125°C (Et2O), 285°C (dec., hydrochloride) [1]

[α]D −30° (EtOH)

IR: 1650 [1]

MSm/z: 244(M+, 90), 243(66), 229, 215, 172, 160, 146, 136(100), 122, 109, 95, 67, 55 [1, 2]

1H NMR(CCl4): 2.71(q, J = 15.2, 11.5, Ha-17), 4.27(q, J = 15.2, 5.4, He-17), 5.75(q, J = 6.8, 1.8), 6.06(q, J = 9.5, 1.8), 7.03(q, J = 9.5, 6.8) [1]

X-ray(tetrahydro): [3]

Pharm./Biol.: Not very active [4]

References

  1. 1.
    T.E. Monakhova, O.N. Tolkachev, V.S. Kabanov, M.E. Perel’son, N.F. Proskurnina, Chem. Nat. Comp. 10, 477 (1974)CrossRefGoogle Scholar
  2. 2.
    Yu.K. Kushmuradov, F.Sh. Eshbaev, A.K. Kasymov, S. Kuchkarov, Chem. Nat. Comp. 15, 306 (1979)CrossRefGoogle Scholar
  3. 3.
    B.T. Ibragimov, S.A. Talipov, T.N. Tishchenko, Yu.K. Kushmuradov, T.F. Aripov, S. Kuchkarov, Chem. Nat. Comp 15, 517 (1979). Chem. Nat. Comp., 17, 546 (1981)CrossRefGoogle Scholar
  4. 4.
    T. E. Monakhova, Author’s Abstract of Candidate’s Dissertation, Moscow, 1975Google Scholar

Copyright information

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