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Leontine

Reference work entry

CAS Registry Number: 6783-60-4 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Quinolizidine Alkaloids

Biological sources: Leontice alberti, L. darwasica, L. ewersmannii

C15H24N2O: 248.1889

Mp: 107–108°C (Et2O), 258°C (perchlorate), 292°C (dec., methiodide), 179°C (picrate) [1]

[α]D −78° (EtOH) [1]

Solubility: very sol. H2O, CHCl3, EtOH, MeOH, Me2CO; spar. sol. pet. ether [2]

IR: 3010, 2950, 2860, 2820, 2760, 2680, 1626, 1471, 1452, 1423, 1377, 1358, 1339, 1327, 1301, 1290, 1271, 1260, 1248, 1184, 1168, 1151, 1138, 1118, 1105, 1081, 1067, 1052, 1026, 1000, 970, 942, 932, 914, 898, 880, 862, 850, 838, 814 [3]

MSm/z: 248(M+, 58), 247(100), 219(3), 206(2), 205(4), 192(1), 177(34), 162(4), 150(27), 138(2), 137(4), 136(11) [4]

1H NMR: 2.85(H-5) [5]

13 C NMR: [ 6]

Table 1

C-2

55.9

C-7

46.2

C-12

28.4

 3

24.7

 8

26.9

 13

19.4

 4

27.5

 9

24.7

 14

32.8

 5

39.1

 10

56.0

 17

46.2

 6

70.9

 11

60.3

   

References

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    R. Shakirov, M.V. Telezhenetskaya, I.A. Bessonova, S.F. Aripova, I.A. Israilov, M.N. Sultankhodzhaev, V.I. Vinogradova, V.I. Akhmedzhanova, T.S. Tulyaganov, B.T. Salimov, V.A. Tel’nov, Chem. Nat. Comp. 32, 596 (1996)CrossRefGoogle Scholar

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