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Leontidine

Reference work entry

CAS Registry Number: 35721-27-8 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Quinolizidine Alkaloids

Biological sources: Leontice alberti, L. darwasica, L. ewersmannii, L. smirnowii

C14H18N2O: 230.1419

Mp: 119–120°C (pet. ether), 311°C (hydrochloride), 276°C (methiodide) [1]

[α]D −190° (MeOH) [1]

Solubility: very sol. Et2O, C6H6, EtOH, Me2CO, H2O; spar. sol. pet. ether [1,2]

UV: 234, 309(3.70, 3.80) [2]

IR: 2700–2500, 1657, 1552 [1]

IR(hydrochloride): 3410, 3350, 1650, 1571, 1553, 1324, 1314, 1280, 1231, 1200, 1168, 1150, 1119, 1088, 1072, 1059, 1041, 1028, 1020, 994, 970, 950, 935, 914, 905, 894, 868, 856, 806, 745, 735 [3]

MSm/z: 230(M+, 4.8), 160, 146, 96, 84(100) [2]

1H NMR: 4.03(2H, m, H-10), 5.75(1H, d, J = 8, H-5), 6.12(1H, d, J = 10, H-3), 7.04(1H, dd, J = 10, 8, H-4) [2]

ORD: [4]

Synthesis: [2]

References

  1. 1.
    S. Zhen-Shen, A.D. Kuzovkov, Zh. Obshch. Khim. 34, 1969 (1964)Google Scholar
  2. 2.
    S. Iskandarov, R.A. Shaimardanov, S.Yu. Yunusov, Chem. Nat. Comp. 7, 611 (1971)CrossRefGoogle Scholar
  3. 3.
    J. Holubek, O. Strouf, Spectral Data and Physical Constants of Alkaloids (Prague Publishing House, Czechoslovak Academy of Sciences, Heyden & Son Ltd, London, 1966), 2, No. 353Google Scholar
  4. 4.
    S. Iskandarov, R.A. Shaimardanov, S.Yu. Yunusov, Chem. Nat. Comp. 7, 615 (1971)CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2013

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