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Leontalbine

Reference work entry

CAS Registry Number: 6475-07-6 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Quinolizidine Alkaloids

Biological sources: Leontice alberti

C15H22N2O: 246.1732

Bp: 180°C (5 mm Hg), 247°C (perchlorate), 277°C (hydrochloride), 216°C (picrate), 259°C (methiodide) [1]

[α]D −167° (EtOH) [1]

Solubility: very sol. CHCl3; sol. H2O, Me2CO; spar. sol. Et2O [1]

UV: 242(4.20) [1]

IR: 2800–2700, 1670, 1640, 803 [1]

MSm/z: 246(M+, 52), 245(100), 231(1), 217, 203, 175(5), 161(2), 148(3), 134(2), 108(0.7), 97(0.5), 96(0.4), 95(0.8), 83(79), 55(8) [2]

1H NMR: 6.90(1H, s, H-17) [3]

ORD: [4]

Pharm./Biol.: LD50 142 mg/kg (i/v, mice). Ganglioblocking and uterine action [5]

References

  1. 1.
    S. Iskandarov, R.N. Nuriddinov, S.Yu. Yunusov, DAN UzSSR (12), 32 (1964)Google Scholar
  2. 2.
    S. Iskandarov, S.Yu. Yunusov, Chem. Nat. Comp. 4, 90 (1968)CrossRefGoogle Scholar
  3. 3.
    R. Shakirov, M.V. Telezhenetskaya, I.A. Bessonova, S.F. Aripova, I.A. Israilov, M.N. Sultankhodzhaev, V.I. Akhmedzhanovz, V.I. Vinogradova, T.S. Tulyaganov, B.T. Salimov, V.A. Tel’nov, Chem. Nat. Comp. 32, 596 (1996)CrossRefGoogle Scholar
  4. 4.
    A. Zunnunzhanov, S. Iskandarov, S.Yu. Yunusov, Chem. Nat. Comp. 10, 371 (1974)CrossRefGoogle Scholar
  5. 5.
    A. G. Kurmukov, M. B. Sultanov, DAN UzSSR, (12), 26 (1965)Google Scholar

Copyright information

© Springer Science+Business Media New York 2013

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